Depression, Alcoholism, and Genetic Alcohol Sensitivity Regulated by ALDH2 and ADH1B Polymorphisms among Japanese Community-Dwelling Adults

Archives of Depression and Anxiety
Research Article
Background: Although strong association between drinking and depression as well as alcoholrelated disorders (ARD) has been reported, the relationship between potential ability to drink (genetic alcohol sensitivity) and depression or ARD is unclear. Genetic alcohol sensitivity is regulated by two alcohol metabolic enzyme genes, ADH1B and ALDH2 polymorphisms. We have already evaluated the association between depression and these polymorphisms in Japanese white-collar workers. Current study expanded this issue on community-dwelling relatively older adults.
http://www.peertechz.com/Depression-Anxiety/pdf/ADA-2-113.pdf
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