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Showing posts from July, 2015
International Journal of Nanomaterials, Nanotechnology and Nanomedicine Commentary Graphene Solar Cells-Will it be the Ultimate Power Converter? Solar cells or photovoltaic (PV) cells involve the direct conversion of light energy into electrical energy. PV cells are basically p - n junctions made from layers of semiconducting materials. Under light illumination, either free electron-hole pairs are generated within the bulk of the layers and subsequently separated through the internal electric field across the depletion layer of the junction (in conventional solar cells), or exactions are created and simultaneously separated across a hetero-interface (in excitonic solar cells), thus producing an open-circuited photo voltage [ 1 1. Green MA (1982) Solar cells: operating principles, technology, and system applications. Prentice-Hall, Inc., Englewood Cliffs, NJ, USA , 2 2. Brian AG (2003) Excitonic solar cells. Phys. Chem. B 107: 4688–4698. ]. Upon connection with an exte
International Journal of Vascular Surgery and Medicine Editorial Endovascular Interventions for Infra-Inguinal Arterial Disease: Collecting Evidence to Expand Indications Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis, with a prevalence of 29% in those older than 70 years or aged 50-70 years who are either smokers or diabetic [1,2] . The majority of persons with this condition are asymptomatic, and less a fifth report typical intermittent claudication [3] . The literature shows us that the risk of limb loss for those who do not have diabetes is 2% or less [4] and, also, that this risk increases three-fold in patients with diabetes requiring pharmacological therapy (oral or insulin) [5] .  http://www.peertechz.com/Vascular-Surgery-Medicine/pdf/IJVSM-1-103.pdf
Archives of Pulmonology and Respiratory Care Case Report Different Levels of Exhaled Nasal Nitric Oxide in Patients Diagnosed with Primary Dyskinesia Background: Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormally beating cilia.  In these patients levels of nasal nitric oxide (nNO) are lower than those observed in healthy subjects.  Objectives: We recorded the nNO levels in PCD patients in order to use those nNO measurements in the screening and identification of patients with symptoms suggestive of disease PCD disease. Methods: We measured nasal NO in 36 PCD patients (3 uncooperative younger children and 33 cooperative adult patients) and did a nNO re-evaluation after 12 months in patients with higher levels of nNO. Results: Twenty-seven PCD patients showed very low nNO levels (29.1 ppb) and nine cooperative patients had high nNO levels (583.3 ppb, p<0.001) (T0); the PCD patients with high nNO levels were re-evaluated after 12 months
Global Journal of Medical and Clinical Case Reports Research Article   Gender Inequalities in Everyday Life Background: Gender inequalities continue in all walks of life for all women, urban rural. Objective: was to know gender differences in everyday life of women. Material methods: Thousand non-pregnant and thousand, pregnant women were interviewed. Results: The information revealed that around 90% pregnant, nonpregnant women, 25% men went to bed late, got up early. Women did all household chores, without any help from husbands. Grocery was brought by 269 nonpregnant, 78 pregnant women. Firewood was collected by 58% woman of 575, households where firewood was used 45% of 513 pregnant women’s families. Of women who worked outside 61% of 656 nonpregnant, 93% of 353 pregnant did all household work also Age, education, occupation did not make any difference in gender inequality of everyday life. Conclusion: All household chores are performed only by women even dur
Journal of HIV for Clinical and Scientific Research Short Communication Pseudomembranous Candidiasis Indicates High Level Drug Resistance among Patients on Antiretroviral Treatment in Nairobi East District, Kenya Objectives: The aim of this study was to determine antiretroviral drug resistance patterns in patients on long-term antiretroviral therapy presenting with OPC. Methods: An exploratory survey was performed among HIV-infected patients on ART for minimum of 24 months presenting with OPC in Nairobi, Kenya. Type (pseudomembraneous or erythematous candidiasis, angular cheilitis) and previous episodes of OPC, CD4-cell counts, duration, regimen and adherence on ART were compared between patients with high ( > 1000copies/ml) and low HIV-RNA levels. Genotypic resistance testing was performed on those with high viral loads. Results: Out of (n=45) patients with OPC, (n=28; 62%) had high HIV-RNA levels. The (n=28) patients who mostly presented with pseudomembraneuos candi
Peertechz Journal of Cytology and Pathology Review Article Diabetes Mellitus and Regenerative Medicine: New Possibilities for the Regeneration of β Cells and Treatment of Diabetic Foot Ulcer Diabetes mellitus is a very common disease that affects a large number of people in the world and whose treatment is very expensive, also due to its complications. Diabetes is associated with many complications and among them the formation of diabetic foot ulcers is a serious problem. Regenerative medicine, defined as a field that can repair, regenerate or replace cells or tissue, can have a very important role in the treatment of this pathology. Over the years, new protocols to reconstruct β cells to produce insulin have been tried out, solving the problem that characterizes the disease. The diabetic foot ulcer is a very serious complication that is usually localized on pressure points and it can lead to the need to amputate the limb. The diabetic patient is characterized by an impaired abil
Peertechz Journal of Clinical Pharmacology and Clinical Pharmacokinetics Editorial Animal Simulation in Under/Post Graduate Studies: It’s Effect in Clinical Pharmacology Research Animal experimentation was successfully taken an important part of the curriculum of the students of medicine, pharmacy, nursing, dentistry, veterinary, and even to basic sciences like life sciences, zoology etc . The objective of the animal experiments was to develop skills for performing in-vivo experiments and to correlate the findings with theoretical concepts as well as in vitro results with prior permission to Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA). However by considering the seriousness of declining of wild life, the University Grant Commission (UGC) decided to stop the animal experimentation for both the under and post graduate levels and noticed accordingly [1] . Therefore redundant animal experiments are now trying to replace with the Computer As
Archives of Clinical Gastroenterology Case Report Colon Lipoma Benign lesions of the colon are infrequent and with a low percentage of appearance. Colon lipomas are in the third place of benign tumors after adenomas and smooth muscle [ 1,5 ]. Colonic lipomas are benign non epithelial tumors of soft texture and mesenchymal origin; generally they grow from mature adipocytes. Lipomas can appear in the entire gastrointestinal tract. They are generally asymptomatic, but when symptomatically, bleeding and obstruction can appear [ 2,4 ]. Its clinical diagnosis is difficult, signs and symptoms include abdominal pain, obstruction, lower gastrointestinal bleeding, diarrhea, constipation, and intussusception [ 5 ]. These tumors are found in endoscopies, radiological exams, surgical interventions, and autopsies. We present 2 cases of colon lipoma. http://www.peertechz.com/Clinical-Gastroenterology/pdf/ACG-1-104.pdf
Archives of Clinical Gastroenterology Research Article The Effect on Gastric Emptying of Telaprevir-Based Triple Therapy for Chronic Hepatitis C Patients Aim: We evaluated food intake in telaprevir-based triple therapy (telaprevir, pegylated-interferon, and ribavirin) and its relation to Gastric Emptying (GE). Methods: 17 patients   received telaprevir combined with pegylated interferon plus ribavirin. The GE study was carried out using the 13 C -acetate breath test and GE time was expressed as the peak time of 13 CO 2 excretion (Tmax). Results: The average food intake was 1,851 ± 91, 1,338 ± 537 and 1,453 ± 537 kcal at 0, 1, and 2 weeks after the start of treatment, respectively, showing a significant decrease compared to that before treatment (p < 0.01 and p < 0.05, paired t-test). The averages of Tmax values at 0, 1, and 2 weeks after the start of treatment were 48.4 ± 14.3 min, 56.9 ± 18.4 min and 58.0 ± 19.9 min, respectively. There was a significant diff
International Journal of Clinical Endocrinology and Metabolism Research Article Glutamic Acid Decarboxylase Autoantibodies Role in Reclassifying Diabetes of Adulthood in Basrah Aim: To determine the prevalence and phenotypic characteristics of diabetes subtypes based on glutamic acid decarboxylase autoantibodies (GADA) status in those newly presented diabetic to the Al-Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC) in Basrah, Southern Iraq. Methods : The study design is cross-sectional and includes adult diabetic patients if they are free of insulin treatment for at least 6 months from diagnosis and to be 30 years of age and over from the period of January 2013 to March 2013. Results: Of our diabetics with age 30 years and more, 26.4% were GADA-positive. The only significantly higher variables seen more among GADA-positive diabetes groups were normal weight and current insulin uses. GADA-positivity was not associated with gender, age, BMI, family hist
International Journal of Clinical Endocrinology and Metabolism Case Report An Analytical Study for Early  Diagnosis and Treatment of  Infants & Children Suffering From Congenital Hypothyroidism in China Objective: To study the clinical and laboratory characteristics of children suffering from congenital hypothyroidism in China. Method: 455 cases of congenital hypothyroidism infants were collected from 5 articles were published in 4 china medical journals. Different screening methods were adopted, like enzyme immunoassay assay and filter paper dried blood biotin-avidin  enzyme notation to test TSH, FT3 、 FT. All the collected children treated by oral thyroxin tablets for long period and regular follow-up was done. Clinical follow up for any signs of hypothyroidism and also detection of I.Q of those children. Results: Markedly effective group: IQ > 70%, height, constipation, lethargy, abdominal distension, jaundice and other symptoms and signs were improved after tr
Global Journal of Anesthesiology Case Report Peri-Operative Takotsubo  Cardiomyopathy: A Case Series Takotsubo Cardiomyopathy (TC) is a reversible, stress-induced, non-ischemic cardiomyopathy associated with temporary weakness of the myocardium and midventricular or apical ballooning.1, 2 Angina, ST abnormalities, elevated troponins, ventricular asynergy, CHF, and decreased EF are all components of TC. The unique finding is that they occur on the absence of CAD.3 In this case series with IRB approval we report three cases of post-operative cardiac symptoms that all resulted in a diagnosis of TC. http://www.peertechz.com/Anesthesiology/pdf/GJA-2-112.pdf

Alteration of the Methylation Status of Urokinase Plasminogen Activator (uPA) is involved in Proliferation and Invasion of Nasopharyngeal Cancer Cells

Archives of Otolaryngology and Rhinology Research Article Alteration of the Methylation Status of Urokinase Plasminogen Activator (uPA) is involved in Proliferation and Invasion of Nasopharyngeal Cancer Cells The extracellular matrix degradation is the most important step in the process of tumor cell metastasis. Urokinase-type plasminogen activator (uPA) can catalyzes the conversion of the inactive zymogen plasminogen to the active broad-spectrum plasmin, which degrades a number of matrix proteins and also activates other proteases, including some matrix metalloproteinases. http://www.peertechz.com/Otolaryngology-Rhinology/pdf/AOR-1-104.pdf 

Distribution of S. mutans and S. sorbinus in Caries Active and Caries Free Children by PCR Approach

International Journal of Oral and Craniofacial Science Research Article  Distribution of S. mutans and S. sorbinus in Caries Active and Caries Free Children by PCR Approach Background: Streptococcus mutans (S. mutans) and Streptococcus sorbinus (S. sorbinus) have been considered to be the most important micro-organisms associated with dental caries. Therefore, purpose of this study is to detect and correlate the presence of S. mutans and S. sobrinus in the dental plaque of caries free and caries active children, by using Polymerase chain reaction (PCR) method. http://www.peertechz.com/Oral-Craniofacial-Science/IJOCS-1-105.php  

Emotional Well-Being in Anorexia Nervosa: Negative Affect, Sleeping Problems, Use of Mood-enhancing Drugs and Exercise Frequency

Archives of Depression and Anxiety  RESEARCH ARTICLE Emotional Well-Being in Anorexia Nervosa: Negative Affect, Sleeping Problems, Use of Mood-enhancing Drugs and Exercise Frequency The purpose of this study was to ascertain emotional well-being among patients presenting ninety anorexia nervosa (AN) and healthy age-matched controls using the Positive Affect and Negative Affect Schedule and the Emotional Well-Being Scale together with background health information. The results indicated that AN patients displayed higher levels of negative affect and negative emotions, more stress and depression, greater sleeping problems, pain, and use of analgesics and mood-enhancing drugs, as well as lower levels of positive affect and positive emotions, compared to the age-matched healthy controls. http://www.peertechz.com/Depression-Anxiety/ADA-1-101.php    

Multipleloci Variable-number Tandem Repeat Typing of Clinical Mycobacterium tuberculosis Isolates from Zunyi, Guizhou Province of China

Journal of Clinical Microbiology and Biochemical Technology  Research Article Multipleloci Variable-number Tandem Repeat Typing of Clinical Mycobacterium tuberculosis Isolates from Zunyi, Guizhou Province of China Introduction: Due to the emergence of multidrug/extensively drug-resistant TB and the lack of new anti-TB drugs, tracing the infectious source and monitoring the transmission of drug-resistant TB strains have become critically important.     http://www.peertechz.com/Clinical-Microbiology-Biochemical-Technology/JCMBT-1-101.php   

Beta-(1,3/1,6)-D-glucan Helps to Decrease Oportunistic Infections in Crohn's Disease Patients Treated with Biological Therapy

Archives of Clinical Gastroenterology  Research Article Beta-(1,3/1,6)-D-glucan Helps to Decrease Oportunistic Infections in Crohn's Disease Patients Treated with Biological Therapy Background: Secondary intercurrent infectious in patients with inflammatory bowel diseases (IBD) represent a very important problem in daily clinical practice because of their significant contribution to quality of life and work ability.   http://www.peertechz.com/Clinical-Gastroenterology/ACG-1-102.php

Diagnosis and management of primary hypothyroidism in Traditional Chinese medicine (TCM) and Traditional Indian Medicine (Ayurveda)

International Journal of Clinical Endocrinology and Metabolism Mini Review  Diagnosis and management of primary hypothyroidism in Traditional Chinese medicine (TCM) and Traditional Indian Medicine (Ayurveda )   Primary hypothyroidism is one of the most common endocrine disorders. TCM and Ayurveda are the two giant ancient systems of medicine flourished in China and Indian sub-continent respectively. The term like hypothyroidism is not mentioned in both classical literatures of TCM and Ayurveda but the features nearest to hypothyroidism are described in both.   http://www.peertechz.com/Clinical-Endocrinology-Metabolism/IJCEM-1-103.php

MicroRNAs in Oncology

Global Journal of Biotechnology and Biomaterial Science Editorial MicroRNAs in Oncology MicroRNAs (miRNAs) are a family of short non-coding RNA molecules which contain about 18-24 nucleotides. miRNAs play significant regulatory roles in biological processes (cell proliferation, differentiation, survival and motility). http://www.peertechz.com/Biotechnology-Biomaterial-Science/GJBBS-1-103.php
Journal of HIV for Clinical and Scientific Research Review Article Adherence to Early Infant Diagnosis Testing Algorithm, a Challenge to Early Infant Diagnosis Program in Resource Limited Settings of Uganda http://www.peertechz.com/HIV-Clinical-Scientific-Research/JHCSR-2-111.php
Journal of Gynecological Research and Obstetrics Research Article Prevention of Brachial Plexus Injuries at Birth Medicine is a fast evolving even if inexact science. Built in ancient times upon insightful observations of Egyptian, Greek and Arabic physicians [ 1 1. Lyons AS, Petrucelli RJ II (1978) Medicine. An Illustrated History. Harry N. Abrams, Inc., New York. ], its progress was spearheaded by European (mainly British, French, German and Austrian) scientists after the middle ages. If the assignment of Nobel prizes is a guideline is this regard, in the last century the leadership was taken over by the United States. Both physicians and lay persons may be inclined to assume therefore, that the achievements of medical research are utilized in America in everyday practice and that progress runs parallel in all branches of medicine. As far as obstetrics is concerned these assumptions have limited validity at best. During the last century maternal and perinatal morta
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