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Showing posts from October, 2015

Autonomic Innervation from the Aortic Root Ventricular Ganglionated Plexi to the Pulmonary Vein: A Novel Pathway

Journal of Cardiovascular Medicine and Cardiology Research Article Abstract  Background: Autonomic nerve innervation pathway from the ventricular GP to the pulmonary veins (PV) remains unclear. Aim: This study investigates the autonomic innervations from aortic root ventricular GP to the PVs. Nissl’s staining and fluorescent dual label staining were performed to determine the neuron structure in the aortic root GP in five dogs. Avidin Biotin Complex (ABC) staining were performed to study the efferent autonomic pathway from the aortic root GP to the PVs. Results: Adrenergic and cholinergic neurons were both present in the aortic root GP, with the majorities were cholinergic. ABC positive nerve fibers that contained both cholinergic and adrenergic neurotransmitters penetrated directly from the aortic root GP to the left PVs. Conclusion: Autonomic innervation of the Left PVs is partly originated from the aortic root ventricular GP .  http: //www. peertechz. com/Cardiovascular-Medici

Direct Composite Laminates - A Case Report

Journal of Dental Problems and Solutions Case Report Abstract Rehabilitation of lost dental aesthetic is one of the most important concerns for contemporary dentistry. Conservative treatment modality along with aesthetic approaches, such as direct and indirect laminate veneer restorations were the treatment of choice. Laminate veneers are restorations to correct aesthetic deficiencies and discolorations. Direct laminate veneers involve the application of a composite material directly to the prepared tooth surface. This case report discusses the composite mirroring using direct composite laminate veneer technique application to the re-established the aesthetic problems related to discolorations in anterior region . http: //www. peertechz. com/Dental-Problems-Solutions/ pdf/JDPS-2-116.pdf

Middle Aortic Syndrome: A Case Report and Review of the Literature

Global Journal of Medical and Clinical Case Reports Case Report Introduction  Coarctation of the aorta is a relatively common defect that accounts for 5-8% of all congenital heart defects and is characterized by discrete medial thickening with superimposed neointimal tissue, leading to aortic lumen narrowing of different degrees.  www. peertechz. com/Clinical-Case-Reports/pdf/ GJMCCR-2-119.pdf

Impact of Early Nasal Obstruction in Histological Development of and Physiological State

International Journal of Oral and Craniofacial Science Research Article Abstract  Introduction: Nasal obstruction is a risk factor in sleep-disordered breathing with a negative impact on the quality of life in humans Objective: In this study we determined whether histological development of olfactory bulb development could be influenced by an early temporary (3 d) nasal obstruction associated with physiological state. Methods: The rats were killed at specific time points after surgery. Plasma samples were taken for biochemical analyses, and histological measurements were performed. Shortly after nasal obstruction, the volumes of external plexiform (CPE), internal plexiform (CGI), and granule cell (CGr) was measured in both sexes of test rats compared with controls. Results and Conclusion: Reversible nasal obstruction was further associated with reduced dimensions of the volumes of CPE (male: 55%; female: 37%), CGI (male: 49%; female: 34%) and CGr (male: 70%; female: 47%). Basal cor

Surgery in Peyronie’s Disease: Our Experiences with Tunica Plication, Plaque Incision and Grafting with Gore-Tex, and Satisfaction Degree of the Patients

Archives of Renal Diseases and Management Research Article Abstract Peyronie’s disease is a relatively common condition, with an incidence of 3-9%. It is often associated with diabetes and erectile dysfunction (ED). This condition causes a penile deformity that can affect sexual penetration and lead to psychological disorders because of the difficulty in coping with the situation. Sometime the surgery does not satisfy the patients; we tried to evaluate this aspect of the disease. Materials and methods: We treated 46 patients for recurvatum penis secondary to Peyronie’s disease. The clinical examination involved an accurate medical history, a physical examination to identify the plaque, ultrasonography to detect calcified plaque, and a photograph of the erect penis to document the recurvatum and sandglass deformity. In the case of ED, we administered the IIEF-5 and performed intracavernous injection of PGE1; in patients eligible for grafting, we also carried out a dynamic echo colou

Antibacterial Effects of Herbal Compounds against Acinetobacter baumannii Isolated from Hospital of Tehran, Iran

Global Journal of Infectious Diseases and Clinical Research Research Article Abstract  Increasing isolation of multidrug-resistant Acinetobacter baumannii (MDR) has been reported in worldwide and it is recently one of the most difficult nosocomial acquired gram-negative pathogens to control and treatment. These bacteria are one of ESBL producing that great potential have for the rapid development of antibiotic resistance. Use of medicinal herbaceous drugs recommended for treatment since ancient periods. Humans have been used and realize their beneficial effects. With the increase in population and urban growth, reduced use of synthetic drugs, many of these of medicinal herbs have been replaced. Because of Satureja, Origanum vulgare and Thyme essence has antimicrobial properties so can be used against infections caused by MDR Acinetobacter baumannii. In this study the antimicrobial effects of Satureja, Origanum vulgare and Thyme essence on drug-resistant strains of Acinetobacter bau

Compulsive Bowel Emptying and Rectal Prolapse in Eating Disorders. Presentation of Two Cases

Archives of Depression and Anxiety Case Report Abstract Eating Disorders are a heterogeneous group of complex psychiatric disorders that affect physical and psychological functioning, thus compromising life itself. They are often characterized by extreme preoccupation with food, caloric intake and expenditure as well as bodily weight and shape. Additionally, individuals present several forms of recurrent compulsive behavior, such as frequent weighting, body checking, and eating rituals. In many cases food consumption is considered a” failure” and its presence in the body “harmful and even “toxic” leading the individual to adopt a wide variety of purging behaviors in order to achieve a state of mental and physical “cleanliness” Two cases of compulsive bowel emptying, one suffering from Anorexia Nervosa and one suffering from Bulimia Nervosa, are presented. The compulsive bowel emptying behavior compromised of repeated and/or prolonged voluntary tension of the abdominal and pelvic mus

Seasonal Changes of Microbial Load in Some Sea Foods from Buguma and Ekerekana Creeks, Niger Delta, Nigeria

Peertechz Journal of Environmental Science and Toxicology Research Article Abstract  Background and Aim: Niger delta environment has been exposed to organic and inorganic contaminants from industries and domestic wastes, thereby enhancing the capacity of the ecosystem into harboring a sizeable population of microorganisms. Most of these microorganisms are found in the water column, bottom sediment and water film, resulting in their elevated levels in seafood. Proper understanding of the transfer of microorganisms through the food web is essential to predict the exposure of seafood consumers to possible health consequences associated with its consumption in the coastal areas. Hence, the present study examines the microbial content of some sea foods such as: periwinkle (Tympanotonus fuscatus); mudskipper (Periophthalmus papilio); mullets (Liza falcipinis) Oyster (Crassotrea gasar) and water from Ekerekana and Buguma creeks, in the Niger delta, Nigeria. Methods: Seasonal variations in

Application of Cone Beam Computed Tomography to Conventional Radiotherapy: Limited Angle of Projections for Lymph Nodes Located above or below the Collarbone

International Journal of Radiology and Radiation Oncology Research Article Abstract  Various techniques are used in image-guided radiotherapy (IGRT). Cone beam computed tomography (CBCT) is widely used in IGRT on linear accelerators. The increased accuracy of IGRT enables reducing planning target volume margins and doses to normal tissues. However, for radiation therapies requiring fractionated irradiation, increased exposure dose attributed to CBCT becomes problematic. We investigated the smallest projection angle required to provide target accuracy for CBCT of lymph nodes located above or below the collarbone in breast cancer patients. Phantom and clinical experiments were conducted on the basis of shifts obtained through gray value-based auto-image registration performed using 360° CBCT. Corrected images obtained from decreasing projection angles in 10° increments were compared with a single 360° image. In the phantom and clinical experiments, the smallest projection angle

The Efficacy of Clove Seed Extracts as an Anaesthetic Agent and Its Effect on Haematological Parameters of African Catfish (Clarias Gariepinus)

International Journal of Aquaculture and Fishery Sciences Research Article Abstract Background and Aim: The intensive nature of aquaculture has subjected fish to a number of stressors in the culture medium, anesthetics are widely used to minimize the issue of stress during farming operations and activities. Clove oil is a well known, established and acceptable anesthetics commonly used in aquaculture, this anesthetics is not readily available in developing countries, thus leaving the fish farmers with option of using the locally available plant extracts as anesthetic agent in fish culture. This study therefore assessed the efficacy of aqueous extracts of clove seed and its effect on hematological parameters of the fish. Methods: A total of 300 Clarias gariepinus comprises of 150 juveniles and 150 adult fish were exposed in triplicates to aqueous extracts of clove seed at concentrations of 5.0, 10.0, 15.0, 20.0 and 25.0mg/l at the rate of 10 fish per tank for both juveniles and ad

Mammalian Parasitic Vaccine: A Consolidated Exposition

Journal of Vaccines and Immunology Review Article Abstract Parasites are highly prevalent in livestock worldwide and infect over one fourth of the human population also. Parasites are successful in evading host immune responses, and vaccination can prove to be an effective way to control them. However, currently very few vaccines are available against parasitic infection. Two important limitations in the emergence of effective parasitic vaccines are incomplete understanding of the immunoregulatory pathways involved in immunity, and the lack of precise information regarding host-pathogen interactions. Precise identification of parasite genes and the role of their products in parasite biology may assist in the identification of useful antigens, which could then be produced in recombinant systems. Many recombinant parasitic antigens have been successfully used in livestock and new vaccines are under trail. Numerous vaccine antigens are defined to target a wide range of parasite spec

Pivmecillinam Treatment of Community-Acquired Uncomplicated Pyelonephritis Based on Sparse Data

Global Journal of Infectious Diseases and Clinical Research Research Article Abstract Background: Pivmecillinam has good pharmacokinetic properties for treatment of infections in the urinary tract, and the mecillinam resistance rate in Enterobacteriaceae is very low. In a European guideline pivmecillinam is recommended as a first-line drug for treatment of lower urinary tract infections. In Danish and Norwegian guidelines pivmecillinam is also recommended for acute uncomplicated pyelonephritis, although with very sparse documentation of effect. Objectives: We intended to investigate the therapeutic outcome of pivmecillinam treatment of uncomplicated pyelonephritis caused by Enterobacteriaceae treated by general practitioners (GP’s) in primary care. Material and methods: We included patients clinically diagnosed with pyelonephritis at the GP, urine samples positive for Enterobacteriaceae and empirical treatment with pivmecillinam. We intended to include patients prospectively, but

The Risks of Haemostatic Materials in Tonsillectomy

Archives of Otolaryngology and Rhinology Case Report Abstract Importance: Surgicel is an effective hemostat either for intra or post-operative bleedings, but should be used cautiously in the case of tonsillectomy. Some surgeons choose to leave pieces of surgicel in the tonsils bed for a continuous haemostatic effect. The material when left in the tonsils fossa is no different than other foreign body and put the patient in a significant risk of suffocation. Observations: four years old girl was admitted to the E.R with multiple complaints and rapid deterioration of her physical state few days after tonsillectomy. Bulky Haemostatic Material spheres almost completely blocked the oropharynx. The foreign material was removed and the complaints resolved, with full recovery. Conclusions and Relevance: leaving surgicel impactions in the oropharynx upon completion of tonsillectomy operation should be avoided. http: //www. peertechz. com/Otolaryngology-Rhinology/p df/AOR-1-108.pdf

Pigmentary Disorders; Vitiligo and Melasma in Context of South Asian Countries: A Psychosocio-Cosmetic Challenge

International Journal of Dermatology and Clinical Research Review Article Abstract Vitiligo and melasma are acquired pigmentary disorder of the skin and also the leading cause for dermatologist consultation in South Asian countries like Nepal. Vitiligo vulgaris and melasma are common examples for depigmentary and hyperpigmentary conditions respectively. There are multiple proven medical, surgical and combined modalities of managing them but the challenge in our part of the world with majority of Fitzpatrick skin types III-V is; it remains a psychosocial-cosmetic disease. http: //www. peertechz. com/Dermatology-Clinical-Resea rch/pdf/IJDCR-1-110.pdf

The Roles of Brackish Water Aquaculture in Fish Supply and Food Security in Some Coastal Communities of Rivers State, Nigeria

International Journal of Agricultural Science and Food Technology Research Article Abstract Background and Aim: Fish plays a crucial role in human nutrition and food supply across the globe, particularly among the poor segment of the society. Food fish currently represents the major source of animal protein needed for growth and development, especially among the children and women who are more vulnerable to malnutrition in developing countries. The importance of food to an individual and society cannot be over emphasized, as food is a basic necessity of life and sufficient intake of quality food is imperative for people to live a strong, vibrant and productive life. Considering the importance of fish food, this study therefore assessed the contribution of brackish water fish farming to stable fish supply and food security in coastal communities of Rivers State. Methods: The roles of brackish water aquaculture in fish supply and food security in 10 coastal communities of Rivers St

Increased Survival after Treatment of Canine Hemangiosarcoma with Fenofibrate

International Journal of Veterinary Science and Research Case Report Abstract Hemangiosarcoma (HSA) is a common and highly metastatic tumor that affects predominantly large-breed dogs. The median survival time for dogs diagnosed with splenic HSA without adjuvant chemotherapy after surgery is 86 days. Fenofibrate is an FDA-approved drug commonly utilized to treat high cholesterol and high triglyceride levels in humans. However, fenofibrate has also been shown to possess anti-proliferative and anti-metastatic properties against several aggressive and highly metastatic tumors in vitro and in small animal models. We report a case of a 6.5-year-old dog diagnosed with a splenic hemangiosarcoma and treated solely with micronized fenofibrate, administered orally once a day following splenectomy. The dog survived for over 26 months (804 days) after initial diagnosis without signs of adverse effects due to fenofibrate treatment. http: //www. peertechz. com/Veterinary-Science-Researc h/pd

Structural Differences in Respiratory System and Airway of Parturients

Global Journal of Anesthesiology Editorial Editorial Oxygen consumption increases with increased alveolar ventilation and respiratory alkalosis occurs. Thus, PaCO2 becomes 28-32 mmHg in pregnant women, and this amount is compensated with renal bicarbonate absorption. Preoxygenation can be made slower by inhalation of 100% oxygen for 2-5 minutes. Denitrogenation of the lungs occurs after three minutes [1]. Another method can be applied quickly with 4-8 deep breaths of 100% oxygen [2]. However, for pregnant women who will have a cesarean section under general anesthesia, an oxygen fraction of 1 has been shown to increase fetal oxygenation more compared with the 0.3 or 0.5 FiO2 [3]. As this may lead to free oxygen radicals and apsorbtion atalectesia, 80 % oxygen is recommended. http: //www. peertechz. com/Anesthesiology/pdf/GJA-2-1 16.pdf

Fetal Monitoring in Open Fetal Surgery

Global Journal of Anesthesiology Editorial Editorial Open surgery and fetoscopic surgery are of the safest procedures, whilst the ex-utero intrapartum treatment (EXIT) procedure has lost its significance as a result of the severe complications experienced both by the mother and the fetus. While uteroplacental circulation maintains, the EXIT is performed before delivery. The fetus is to be delivered at the conclusion of the case. A neonatal resuscitation area and two operating rooms are needed. Significant uterine relaxation is required for open midge station surgery. The risk for rapid bleeding and hemodynamic instability are the common accompanying parts of this procedure. It still continues to be a process done in certain centers not only in United States but also in Europe [1]. http: //www. peertechz. com/Anesthesiology/pdf/GJA-2-1 17.pdf

Intravenous General Anesthesia for Patients with Neurological Disorders

Global Journal of Anesthesiology Editorial In dental practice, intravenous general anesthesia is useful for patients who are difficult to treat when not sedated such as those with neurological disorders [1]. http: //www. peertechz. com/Anesthesiology/pdf/GJA-2-1 18.pdf

The Stent Evolution in Colo-Rectal Emergencies

Journal of Surgery and Surgical Research Research Article Summary Introduction: The appearance of a framework for occlusive colorectal tumor raises complex issues and difficult. We need to ensure a resumption of normal bowel function in patients often in extreme conditions. Emergency surgery flounders in a derivation and a resection with restoration of intestinal transit. The progress of digestive endoscopy can now make available a medical procedure can solve the framework occlusive both as palliation both as a bridge to safer surgery. The purpose of this study is to evaluate the indications and limitations of the method of colon prosthesis with selfexpandable stents. http: //www. peertechz. com/Surgery-Surgical-Research/ pdf/JSSR-1-112.pdf

Scientific Evidence Regarding the Quality of Life of Total Laryngectomees

Archives of Otolaryngology and Rhinology Review Article Abstract Introduction: The loss of laryngeal voice after total laryngectomy can have an impact on the quality of life and communication of affected individuals. Postoperative phonatory methods may promote advantages in oral communication and reduce the functional, organic and emotional changes experienced by the patients. On this basis, the objective of the present study was to review the literature in order to determine the impact on the quality of life of total laryngectomees according to the form of rehabilitation chosen after the procedure and to identify the protocols most frequently used to assess the quality of life of these individuals. http: //www. peertechz. com/Otolaryngology-Rhinology/p df/AOR-1-107.pdf

Direct and Bystander Effect on Cervix Cancer Cells (SiHa) Exposed to High Dose-Rate Gamma Radiation Sourced from Ir192 Used in Brachytherapy

International Journal of Radiology and Radiation Oncology Research Article Abstract Introduction: Brachytherapy is a preferred choice of radiotherapy in the treatment of sensitive tissues cancer like intestine and gonad. The treatment is expensive because of the frequent replacement of radionuclide sources. A better understanding of cell killing and the cellular responses at different dose rates, might aid in tumor cell killing with fewer doses thereby enhancing a better prognosis. Methods: The cervix cancer cell line was irradiated with doses ranging from 2Gy-10 Gy at three different dose-rates as used in brachytherapy along with unexposed sample as control. The biological effects of different doses and dose rate of the cells was assessed by measuring its cytotoxicity, genotoxicity and clonogenic ability of exposed cells. The bystander effect was examined by coculturing the exposed tumor cells with the unexposed normal blood lymphocyte and vice-versa. Results: A significant and

Hypertension and Cardiovascular Risk Factors in Young University Students from Quito, Ecuador

Archives of Clinical Hypertension Research Article Abstract Introduction: Hypertension is the most common chronic non-contagious disease. High blood pressure is an important risk factor for premature mortality and contributes to the development of heart disease, stroke and kidney failure. In spite of the fact that it is consider to be an adult disease, the frequency in young people has increased. Methods: All students enrolled in first, second and third semester of the Medical School, Faculty of Medical Sciences – Universidad Central del Ecuador, period October 2014 - March 2015 were invited to participate. Body mass index was calculated; waist circumference and blood pressure were measured. The diagnosis of hypertension was made using recommended criteria by the ATP III, IDF and JNC 7. Blood chemistry including urea, glucose, creatinine, uric acid and lipid profile were determined. Results: 883 college students in a range of 17-25 years were included; the average age was 19.3 ±

Mediastinal Tuberculosis Lymphadenitis during Anti-TNF Therapy - Case Report

Archives of Clinical Gastroenterology Case Report Abstract Tuberculosis is described during the use of monoclonal antibodies against tumour necrosis factor (TNF) for Crohn’s disease treatment. We report a case of a 44 year old man that developed fever, night sweats and weight loss during immunosuppressive and anti-TNF therapy for Crohn’s disease . After extensive investigation we performed mediastinoscopy with biopsy of the paratracheal lymph node. A histopathological study revealed caseous necrosis. The patient improved after therapy against tuberculosis. During anti-TNF therapy, the diagnosis of tuberculosis may be mainly difficult when an atypical location is present. Clinical skills are important mainly in countries where tuberculosis is endemic. http: //www. peertechz. com/Clinical-Gastroenterology/ pdf/ACG-1-108.pdf

Regulatory Mechanisms of Bone Development and Function

Peertechz Journal of Cytology and Pathology Review Article Bone is metabolically active organ where 10% of it is normally and constantly replaced. Bone constitutes the trabecular or spongy bone (25%) and cortical or compact bone (75%). Trabecular bone is metabolically active and forms the internal supportive elements of the bone. The outer capsule is made up of cortical bone and is particularly present in the shafts of long bones. At the structural level, two different forms of bone can be distinguished, i.e. cortical or compact bone− which forms the diaphysis of long bones and provides protection for the medullary cavity− and trabecular, cancellous, or spongy bone, which is found at the ends of the long bones (epiphyses). The total skeleton comprises about 20% of trabecular bone. Trabecular bone has a porosity of 50%– 90%, while cortical bone of 10% [1]. http: //www. peertechz. com/Cytology-Pathology/pdf/PJC P-1-102.pdf

Co-Administration of PPV23 and Influenza Vaccines in England and Wales: A Study Based on the Royal College of General Practitioners Sentinel Surveillance Network

Journal of Vaccines and Immunology Research Article Abstract  Background: Pneumococcal disease is an infection caused by a bacterium called Streptococcus pneumonia which can lead to life-threatening invasive pneumococcal diseases. In the UK, pneumococcal vaccination is targeted at those most at risk of serious disease: infants, older people and those with risk factors. It has been proposed that PPV23 be co-administered with influenza vaccine during seasonal vaccination to maximize uptake. This study aimed to estimate 1) the UK prevalence of pneumococcal risk co-morbidities 2) corresponding pneumococcal vaccine administration rates 3) rates of vaccination co-administration and 4) frequency of pneumococcal revaccination. Methods: To gather evidence on current vaccination practice in the UK and to quantify the rates of co-administration of influenza and pneumococcal vaccination, data was collected from general practices in the Royal College of General Practitioners sentinel surveill

Probiotics and Bone Health: It takes GUTS to Improve Bone Density

International Journal of Immunotherapy and Cancer Research Review Article Abstract Probiotics are a class of symbiotic bacteria whose administration in adequate amount provides health benefits to the host by altering the composition of gut microbiota. The gut microbiota is known to regulate both the host immune system and metabolism, leading to increased bone mass by inhibiting bone resorption. Ovariectomy induced estrogen deficiency which mimics postmenopausal osteoporosis in women leads to enhanced bone inflammation and resorption. Recently it has been reported that different strains of bacteria (e.g. Lactobacillus, Bifidobacteria etc.), have important role in gut-bone regulation in ovariectomized mouse. Thus administration of probiotics can open up new avenues in treatment of various inflammatory bone conditions such as osteoporosis and rheumatoid arthritis by modulating the delicate balance between the gut microbiota and immune system. http: //www. peertechz. com/Immunother

Clinical Aspects of C-Type Natriuretic Peptide on the Cardiovascular System

International Journal of Clinical Endocrinology and Metabolism Review Article Abstract C-type natriuretic peptide (CNP) is one of the three most important members of the human natriuretic peptide family, sharing with them a highly conserved 17-aminoacid ring structure, essential to elicit its biological actions by binding to its specific receptor NPR-B. CNP acts in a paracrine or autocrine way and it is cleared from plasma circulation by the NPR-C receptor. This is one of the reasons why its plasma levels are usually low. CNP is widely spread in human tissues, being localized in a variety of cells such as cardiac and vascular smooth muscle cells, chondrocytes, macrophages, glial cells, and renal, brain and reproductive tissues. In the cardiovascular system, CNP is stored in endothelial cells and exert different actions like vasodilation in large conduction vessels, and anti-proliferative, pro-apoptotic, anti-fibrotic and anti-hypertrophic properties in cardiomyocytes; it also inh

The Value of Positron Emission Tomography/Computerized Tomography Imaging in the Restaging of Differentiated Thyroid Cancers and Evaluation of its Association with Thyroglobulin Levels

International Journal of Clinical Endocrinology and Metabolism Research Article Abstract Purpose: Recently, there have been an increasing number of studies indicating that Florine-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a sensitive method in the evaluation of thyroid cancer. This retrospective study aims to assess the value of FDG PET/CT in the evaluation of thyroid cancer and determine the association between serum thyroglobulin (Tg) levels and FDG PET/CT. Methods: We reviewed FDG PET/CT images of 104 patients with differentiated thyroid cancer (DTC) (28 men, 76 women) whose: (1) iodine-131 (131I) whole-body scanning (WBS) was negative but had elevated Tg levels or (2) Tg level was low, but showed abnormal findings using various imaging methods. Results: The overall sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of FDG PET/CT findings were found to be 95.92%, 87.27%, 87.04%

Lymph Nodes Close to the Thyroid Isthmus Can Masquerade as Malignant Thyroid Nodules in Chronic Lymphocytic Thyroiditis

International Journal of Clinical Endocrinology and Metabolism Case Report Abstract We present a 40 year old lady who was previously reviewed in a different center with a neck swelling and a clinical and biochemical picture of post-partum thyroiditis. She underwent a fineneedle aspiration (FNA) biopsy of a hypoechoic isthmus nodule that was reported as being a follicular neoplasm and diagnostic surgery was recommended. She presented to ourselves for a second opinion. She had clinically improved by this time and on re-do sonography was found to have multiple lymph nodes in close proximity to the isthmus and prominent appearances of thyroiditis, but no suspicious thyroid nodules per se. Follow-up ultrasonography revealed unchanged appearances and on review at the regional thyroid nodule and cancer multi-disciplinary meeting an unanimous consensus was reached that no invasive procedures or treatments were indicated apart from clinical and sonographic monitoring. The likely original

Potential Involvement of Mitochondrial Dysfunction in Major Depressive Disorder: Recent Evidence

Archives of Depression and Anxiety Mini Review Abstract Major depressive disorder (MDD) is a leading cause of morbidity and mortality, and it is a common psychological disorder in the world. Present antidepressants modulate monoamine systems directly or indirectly, because MDD is classically considered as a neurochemical disease, in which monoamine systems are perturbed including serotonin, noradrenaline or dopamine systems. However, recent evidences suggest that MDD is associated with the impairments of synaptic plasticity or cellular resilience to stress. Cellular resilience is maintained by mitochondria with the supplying cellular fuel or ATP. In addition, it is suggested that mitochondrial functions in neurons influence synaptic plasticity. Therefore, impairment of mitochondrial function can be the cause of the MDD. The present review article summarizes the recent evidences about the association between mitochondrial impairment and MDD, and it suggests that improvement of mit

Novel Use of Optokinetic Chart Stimulation to Restore Muscle Strength and Function in a Bed Bound Traumatic Brain Injury Patient that was in a Vegetative State of Unconsciousness: A Case Study

Journal of Novel Physiotherapy and Physical Rehabilitation Case Report Abstract Introduction: Patients with severe traumatic brain injury are known to have poor outcomes. The prognosis is even worse if they remain vegetative or minimally conscious for months. The objective of this case report is to highlight the novel use of optokinetic chart stimulation to improve muscle strength and functional mobility in a patient who was in a vegetative state of unconsciousness for months after sustaining a severe traumatic brain injury and C7 spinal fracture. The patient could not open their eyes and breathed through a tracheostomy tube. Methodology: An optokinetic chart was moved in front of the patient: from side to side, up and down and finally forwards and backwards. This was supplemented with sensory interaction for balance once the patient could stand with assistance. Results: Oxford score improved from absent voluntary movements to 410/410 within one month after treatment had begun. G

Biopolymers for Echiniculture Feeding

International Journal of Aquaculture and Fishery Sciences Research Article Abstract Background: Biopolymers have many fields of application. In Echiniculture they are usually employed to bind trial diets, although a systematic study on the performances of biopolymers as feed binders is lacking. Methods: Several biopolymers (sodium alginate, agar, gellan, apple pectin and citrus pectin with different esterification degree) were employed as binders in the manufacture of biocomposites to be used as Paracentrotus lividus feed. Biocomposites were first produced with varying percentages of feed ingredients (5-25%) and polymers (2-3%), either alone or in blends of two types. Biocomposites were tested for stability, swelling and nutrient release in water. In order to evaluate their palatability, biocomposites were administered to sea urchins and eating activity checked up to 48 h. GI and gonad composition were evaluated in a 14-week rearing trial. Result:Agar and apple pectin gave the be

Residues of Propargite in Tea

International Journal of Agricultural Science and Food Technology Research Article Abstract Propargite is an acaricide extensively used in India for controlling the populations of the red spider mite (RSM) infesting tea. Field experiments were conducted at two places in Tamil Nadu (India) during the dry season to determine the residues of propargite in black tea. Residues were quantified at different harvest intervals of ‘0’ (3 hr), 1st, 3rd, 5th, 7th, 10th and 14th day after acaricide application. Persistence, dissipation pattern, half-life value and safe harvest interval of the acaricide in tea were calculated. Residues of propargite dissipated exponentially after application at both the locations and reached below the CODEX MRL of 5 mg/kg on the 7th day. Regression lines drawn on propargite showed that like other acaricides it followed the first order dissipation kinetics. Half-life values varied from 1.63 to 1.92 days for propargite and a safety harvest interval of 7 days is

Leukemia Cutis

Imaging Journal of Clinical and Medical Sciences Clinical Image A patient of 55 years presented seven days ago a fever. Since 3 days he developed multiple nodular lesions. Dermatological examination revealed pruriginous pinkish and infiltrated plaques, nodules and papules, with firm consistency, disseminated on the trunk .There was no mucosal or nail lesions. The rest of the physical examination was normal. Histology was in favor of leukemia cutis witch correspond to cutaneous localization of acute leukemia. The study of skin lesions allowed a quick diagnosis of the etiology of fever. The care of his leukemia is accompanied by the disappearance of lesions. http: //www. peertechz. com/Clinical-Medical-Sciences/ pdf/IJCMS-2-120.pdf

Peertechz's Policy on word count

Purpose of word count limit Peertechz urges the prominent writers or authors to not only concern with what words to use but also how many words. In Peertechz word count is not a rule but a specified guideline on what length of manuscript is acceptable for submission and publication. Word count is the number of words in a manuscript submitted or to be submitted in the Peertechz’s online journals. Writing according to specified word limits is a skill required to set appropriate assessment outcomes. A word limit for manuscripts give a clear indication of the maximum length of a piece of assessed written work, the amount of work expected and therefore how much detail an author should go into and how they should allocate time to one piece of assessed work in relation to the others. What is included in the word count? Word count includes everything in the main body of text including heading, tables, citations, quotes, lists etc. However the list of reference, appendices and footnot

Management of a Common Iliac Artery Aneurysm Causing Contralateral Iliac Venous Thrombosis

International Journal of Vascular Surgery and Medicine Case Report Abstract  A 73-year-old male patient was diagnosed with thrombotic obstruction of the left common iliac vein (LCIV). Computed tomography imaging revealed a known -under follow-up- isolated aneurysm of the right common iliac artery that seemed to directly obstruct the LCIV. Given the patient’s renal insufficiency as well as the size and anatomy of the aneurysm, the patient underwent open repair. The decision between open and endovascular repair, given the proximal DVT, is a dilemma, considering the risk for pulmonary embolism perioperatively as well as the venous thrombosis outcome postoperatively. Therefore, we present such an unusual case and discuss proper management.   http: //www. peertechz. com/Vascular-Surgery-Medicine/ pdf/IJVSM-1-104.pdf  

Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion Associated with Rhinovirus Infection

Journal of Vaccines and Immunology Case Report Abstract  We report a 7-year-old patient with mild encephalopathy with a reversible splenial lesion (MERS) presenting with recurrent delirious behavior, hallucinations and seizures following common cold. Cranial MRI showed high signal intensity in the splenium of the corpus callosum. Rhinovirus was detected in the nasopharyngeal swab by multiplex PCR. Other respiratory viruses were not detected. Microbiologic tests for Epstein-Barr virus, herpes simplex virus, varicella-zoster virus, cytomegalovirus, measles, mumps, rubella and Mycoplasma pneumoniae were also negative. This is the first reported case of MERS associated with rhinovirus infection.   http: //www. peertechz. com/Vaccines-Immunology/pdf/JV I-1-108.pdf  

Fabrication and Characterization of HER2 Cell Receptor-Targeted Indocyanine Green-Encapsulated Poly (Lactic-co-Glycolic Acid) Nanoparticles

Peertechz Journal of Biomedical Engineering   Research Article Abstract  Introduction: The aim of this study is to fabricate and characterize human epidermal growth factor receptor 2 (HER2)-targeted indocyanine green (ICG)-loaded poly (lactic-co-glycolic acid (PLGA) nanoparticles (HIPNPs). Methods: The HIPNPs were fabricated by a modified emulsification in association with solvent evaporation approach. The size and surface charge of the manufactured nanoparticles were determined by dynamic light scattering technique. The morphology of the HIPNPs was detected by SEM. The activity of surface anchored anti-HER2 antibodies was detected by spectro fluorometry and fluorescent microscopy. The encapsulation rate of ICG, percentage of ICG content, and the degradation efficiencies of entrapped ICG under different temperatures were measured through UVVis spectrometry. Results: All HIPNPs exhibited particulate morphology with size of 302 ± 1.8 nm and surface charge of -15 ± 0.15 mV where the

Comparison of Effects of Flutter Device versus Autogenic Drainage on Peak Expiratory Flow Rate, Oxygen Saturation, Respiratory Rate and Pulse Rate in COPD Patients

Journal of Novel Physiotherapy and Physical Rehabilitation Research Article  Abstract  Purpose: To evaluate the effects of short term treatment of Flutter device and Autogenic Drainage (AD) in patients with chronic obstructive pulmonary disease (COPD). Methods: Thirty male and female COPD patients were randomly assigned into two groups, were trained for the intervention, and then the intervention was performed by them. Peak expiratory flow rate (PEFR), Arterial Oxygen saturation (SpO2 ), Respiratory rate and Pulse rate were measured pre and post. Results: There was no statistically significant difference between the groups. Within group analysis showed that both the treatments were equally effective in improving the dependent variables. Conclusion: Flutter is as effective as the AD. Any of the techniques can be used in COPD patients according to patients and physiotherapist preferences. http: //www. peertechz. com/Novel-Physiotherapy-Physic al-Rehabilitation/pdf/JNPPR-2- 124.pd