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Showing posts from February, 2016

Mitotic Catastrophe - Role in Programming of Cell Death

International Journal of Oral and Craniofacial Science Mini Review The incidence of cancer worldwide is on a rise, accounting it to be the second most common disease, first being the coronary heart disease [1]. The losses of cellular regulation that gives rise to most or all cases of cancer are due to genetic damage. Mutations, in two broad classes of genes – proto-oncogenes (eg, ras) and tumor suppressor genes (eg, APC) – play key roles in cancer induction. These genes encode many kinds of proteins that help control cell growth and proliferation. All human tumors have inactivating mutations in genes that normally act at various cell-cycle checkpoints to stop a cell’s progress through the cell cycle if a previous step has occurred incorrectly or if DNA has been damaged [2].   http://www.peertechz.com/Oral-Craniofacial-Science/pdf/IJOCS-2-111.pdf 

Implications of Vitamin D Deficiency in Chronic Kidney Disease - A Systematic Review

Archives of Clinical Nephrology Mini Review Vitamin D presents interesting pleiotropic effects for the CKD patient (effect and anti-inflammatory properties). Patients with chronic kidney disease (CKD) have impaired endothelial function and the Vitamin D and its analogs may play a role in regulation of endothelial function and inflammation. Therefore, it is increasingly observed that CKD is characterized by a state of chronic inflammation that appears to be linked to oxidative stress, endothelial dysfunction and vascular calcification. http://www.peertechz.com/Clinical-Nephrology/pdf/ACN-1-107.pdf    

Acquired Immunodeficiency Syndrome Revealed by Oral Kaposi’s Sarcoma

International Journal of Oral and Craniofacial Science Case Report Abstract Kaposi’s sarcoma is the malignant proliferation of the endothelial cell vessels. It is a systemic, malignant and multifactor disease. It usually presents initially as violaceous cutaneous lesions. Outside of a known context of an immune deficiency, an isolated oral lesions may not think to Kaposi’s sarcoma. Hence the interest of the histological and immunohistochemical study. This paper reviews one such case of Kaposi’s sarcoma in a 42-year-old woman who present an isolated pigmented lesions of the tongue, related to Kaposi’s sarcoma, without cutaneous or visceral involvement, and which led to the discovery of acquired immunodeficiency syndrome (HIV). The stabilization was obtained with antiretroviral triple therapy.  http://www.peertechz.com/Oral-Craniofacial-Science/pdf/IJOCS-2-110.pdf    

Ruta graveolens Protects Against Isoniazid/Rifampicin-Induced Nephrotoxicity through Modulation of Oxidative Stress and Inflammation

Global Journal of Biotechnology and Biomaterial Science Research Article Abstract  Background and Aim: Drug-induced nephrotoxicity is a renal dyfunction that arises as a result of exposure to nephrotoxic drugs. Anti-tuberculosis therapy can cause nephrotoxicity and permanent kidney damage. The current study was designed to evaluate the possible protective effects of Ruta graveolens L. leaves extract against isoniazid/rifampicin-induced nephrotoxicity in rats. Methods: The experimental rats received isoniazid and rifampicin at dose level of 50 mg/kg, and 50 or 100 mg/kg/day Ruta graveolens leaves extract orally for 45 days. http://www.peertechz.com/Biotechnology-Biomaterial-Science/pdf/GJBBS-1-105.pdf

The Immunologic Relationship between Root Resorptions and Osteoclastic Activity - Literature Review

Global Journal of Infectious Diseases and Clinical Research Review Article Current literature indicates the close relationship between root resorptions and the role of clasts responsible for hard tissue destruction. The process is complex and involves mechanical factors and intense biological activity. Immunological interactions stimulate the recruitment and migration of clasts into a specific area, in order to destroy bone, cementum and dentin. Nevertheless, understanding the whole process will bring light to other questions concerning the role of the immunologic system in other parts of the human body. http://www.peertechz.com/Infectious-Diseases/pdf/GJIDCR-2-108.pdf  

Staged Ultrasound-Assisted Catheter-Directed Thrombolysis for Bilateral Pulmonary Embolism: "All with one Catheter-Technique"

International Journal of Vascular Surgery and Medicine Case Report A 70-year-old male presented with two days increasing dyspnea. His past medical history was notable for deep venous thrombosis with consecutive pulmonary embolism (PE). Diagnostic workup showed normal blood pressure (130/80mmHg), sinus tachycardia with SIQIII-pattern on electrocardiogram, and elevation of troponin (0.22ng/nl). http://www.peertechz.com/Vascular-Surgery-Medicine/pdf/IJVSM-2-109.pdf  

Reciprocal Relationship between Compliance with Post-Op FollowUp and Weight Loss after Bariatric Surgery

Archives of Clinical Gastroenterology Research Article Obesity is a large and growing health problem in the UK with high associated costs to the NHS. Bariatric surgery is proven as an effective treatment for obesity associated with long term weight loss and a reduction in obesity related comorbidities [1]. The NICE guidance highlights the importance of follow-up post-surgery [2].    http://www.peertechz.com/Clinical-Gastroenterology/pdf/ACG-2-110.pdf  

Current Knowledge on Psychic Stress in Surgical Procedures

Peertechz Journal of Biological Research and Development Review Article The incidence of stress among individuals submitted to major surgery is relevant. Although it has been noted that some patients go through the perioperative period without presenting stress, surgical patients have a high probability of presenting one of the four phases of stress. Recognizing the stress phase that affects the patient permits the medical team to act in a more appropriate manner and to propose interventions that will prevent worsening of the disease and an unsuccessful outcome of surgery. The main objective of this paper was to present a review of the most important aspects regarding psychic stress in patients undergoing major operations under general anesthesia. http://www.peertechz.com/Biological-Research-Development/pdf/PJBRD-1-102.pdf  

Lactate Dehydrogenase is involved in but not the Target Antigen in Children with Kawasaki Disease

Journal of Cardiovascular Medicine and Cardiology Research Article Abstract Background:  Kawasaki disease (KD) is an acute vasculitis often complicating coronary arterial lesions, and gradually becomes the leading cause of acquired heart disease instead of rheumatism. Previous studies often regards elevation of serum lactate dehydrogenase (LDH) level as an auxiliary diagnosis marker when judging myocardial diseases. http://www.peertechz.com/Cardiovascular-Medicine-Cardiology/pdf/JCMC-3-121.pdf

Metabolic Associations with Skin Tags

International Journal of Dermatology and Clinical Research Research Article Abstract  Background: Skin tags are small, soft, pedunculated, often pigmented lesions, usually occurring on the eyelids, neck and axillae. There have been a few reports in the literature that the presence of skin tag is associated with different components of the metabolic syndrome. Objective: To evaluate the relationship between components of metabolic syndrome (atherogenic lipid, glucose level, hypertension, and waist circumference) and other metabolic associations with skin tags. Patients and Methods: A total of 51 patients with skin tags aged 16 to 64 years, 13 males (31.37%), 38 females (68.63%) with a mean age of (38.6 ± 12.1 SD); and 50 healthy controls aged 19 to 60 years, 13 males (30%) and 37 females (70%) with a mean age of (37.9 ± 9.4 SD) were examined in dermatology outpatient clinic of Kufa Medical School Teaching Hospital, Najaf, Iraq. Body Mass Index (BMI),waist circumference (WC),blood pre

Ambulatory Monitoring of Blood Pressure in Occupational Hypertension

Archives of Community Medicine & Public Health Clinical Image Clinical Image  Stress is considered to have a strong impact on changes in blood pressure through overproduction of catecholamines during working hours [1,2]. We are presenting the graphical behavior of blood pressure of two patients. In both cases hypertension is present exclusively during working hours. The first graphic correspond to a 39 year old nurse working 7 hours (Figure 1) and the second one, to a 46 year old engineer working from 8:00 am to 22:00 pm. In the second case, this period also included a two hour-lunch break and nap break.  http://www.peertechz.com/Community-Medicine-Public-Health/pdf/ACMPH-2-107.pdf    

Dental Age Estimation Methods in Forensic Dentistry: Literature Review

Peertechz Journal of Forensic Science and Technology Review Article Abstract  Introduction: Age estimation is essential in human identification, but also in civil and pension lawsuits. Teeth maturation is better than other structures and the dental changes provide characteristics which are grouped in different age estimation methods.  Objective: The purpose of this literature review was to present the main methods in age estimation that have been currently used.  Material and Methods: The database searched was PubMed and the terms used were “dental age estimation methods” and “forensic dentistry”. Just papers about dental age estimation methods written in English between 2012 and 2015 were selected.  Results: 67 papers were retrieved through electronic searching, but nine studies were excluded. Conclusion: The most dental age estimation methods were based on developmental stages of the teeth through radiographs and they were applied in children and sub-adults in countries of the

Endodontic Management of Aberrant Root Canal Anatomy in Premolars - A Report of Two Case

Journal of Dental Problems and Solutions Case Report Abstract  Premolars are recognized for their aberrant root canal anatomy. The unique feature of dilacerations and multiple root canals pose utmost challenge in the endodontic management. A clinician is required to have an insight of the morphology of tooth related to its shape, form and structure prior to commencing root canal treatment. This article describes the endodontic management of two cases of aberrant root canal anatomy in premolars.   http://www.peertechz.com/Dental-Problems-Solutions/pdf/JDPS-3-125.pdf 

Adenocarcinoma of Ceruminous Glands: Role of the VMAT

Archives of Otolaryngology and Rhinology Case Report Abstract  Adenocarcinoma of the ceruminous glands is a rare malignancy arising from the glands of the external auditory canal. In most patients it is usually diagnosed as locally advanced disease with a major obstacle for radical surgery. Here, we describe two cases of patients suffering of sudden hearing loss and ipsilateral facial hemiparesis due to tumors arising from the ceruminous glands with primary intracranial involvement and subsequent middle ear infiltration. The patient with localadvanced disease underwent surgery followed by adjuvant treatment, whereas the other patient with advanced disease only to palliative therapy. However, both of them received volumetric-modulated arc radiotherapy (VMAT) resulting in complete remission as adjuvant treatment in the first patients while extending the survival as palliation in the second one. Thus, VMAT appears a suggested approach in this tumor which management is still poorly def

Six Minute Walk Test: Functional Evaluation and Prognosis in Heart Failure

Journal of Novel Physiotherapy and Physical Rehabilitation Editorial The determination of functional capacity is of fundamental importance in monitoring and defining the prognosis of patients with heart failure (HF) may be the six minute walk test (6MWT) is a possibility. The 6MWT was first described by Balke in 1963 [1], since now applied in various clinical conditions, but still without proper standardization. In 2002, the American Thoracic Society (ATS) has established a guideline for performing the 6MWT [2].   http://www.peertechz.com/Novel-Physiotherapy-Physical-Rehabilitation/pdf/JNPPR-2-128.pdf 

High-Voltage Electrically Head Injury Presenting underlying Calvarial Osteomyelitis: Single Indonesian Tertiary Hospital Experience

Journal of Surgery and Surgical Research Research Article Abstract  Objective: To demonstrate the characteristic of high-voltage electrically head injury patients presenting underlying calvarial osteomyelitis. Methods: Retrospectively report of patients high-voltage electrically head injured with calvarial osteomyelitis from January 1st 2011 to December 31st 2013. The demographic variable namely age, sex, place of accident, present of calvarial osteomyelitis, Glasgow coma scale, surgical treatment type, grading of burn injury and total body surface area of burn (TBSA). Results: Eleven high-voltage electrically injured patients presenting with calvarial osteomyelitis, who admitted to the Emergency Unit Department of Neurosurgery Hasan Sadikin Hospital, All patients were males (100%). Their ages ranged between 24 and 51 years (average 23,7 years old) All patient (100%) suffered from calvarial osteomyelitis. Eight patient (77,7%) were high building worker at the time of incident, two

Comparative Analysis of Conventional and Thin Prep Papanicolaou Test. Technical and Economic Aspects

Peertechz Journal of Cytology and Pathology Research Article Abstract  Background: Cervical cancer is the fourth most common cancer and a leading cause of death due to cancer, in female population worldwide. Prevention is performed via the Papanicolaou test. Since 90ies, this test can be performed via two methods: the conventional method, where cells are layered on a glass slide, immediately after their extraction and Liquid Based Cytology (LBC), where cells are stored in a vial containing a special liquid.  http://www.peertechz.com/Cytology-Pathology/pdf/PJCP-1-103.pdf  

Phytoremediation Efficiency of Sorghum Bicolor (L) Moench in Removing Cadmium, Lead and Arsenic

Open Journal of Environmental Biology Research Article Abstract  Heavy metals are a significant problem in municipal wastewater, in soil accumulation and are costly to remove in order to facilitate water use in irrigation. Wastewater, with three heavy metal cations and an iron, was employed in irrigation during the Sorghum bicolor (L) Moench growth period. Results show that the absorption coefficient or bioaccumulation ability of Sorghum bicolor (L) Moench is relegated to certain heavy metals and their concentrations, but not at all to plant tissues in dry ash weight (DAW) scale. Heavy metals absorption was determined in the following order: cadmium = lead > arsenic, and while tissue accumulation based on DAW was equal for cadmium and lead, based on dry weight (DW) all three ions differed. The soil’s ability to accumulate heavy metal ranked as follows: cadmium > lead > arsenic by wastewater quality in this experimvent. These results change many previous ideas about decreas

Optimization of Sintering Conditions for Improvement of Mechanical Property of a-Tricalcium Phosphate Blocks

Global Journal of Biotechnology and Biomaterial Science Research Article Abstract  Bioactive ceramic materials have been under research as bone substitute for several decades. To repair the high-load bearing bones, mainly cortical bones, there is a need for the substitute to possess comparable mechanical strength to cortical bone, of which the compressive strength ranges between 100 and 230 MPa. Two prevailing bone repairing material, β-tricalcium phosphate (β-TCP, β-Ca3 (PO4 )2 ) and hydroxyapatite (HAp: Ca10(PO4 )6 (OH)2 ) have been widely researched and sintered into dense blocks to meet the mechanical requirements. α-tricalcium phosphate (α-TCP, α-Ca3 (PO4 )2 ), a high temperature polymorph of β-TCP, received relatively less attention and α-TCP dense sintered blocks have not been reported yet. In this research, we fabricated α-TCP dense blocks by sintering under various temperatures (1150-1400 °C) and the highest compressive strength was around 230 MPa. Intermediate porous b

Hepatopulmonary Syndrome and Portopulmonary Hypertension in the Same Patient

Journal of Clinical Microbiology and Biochemical Technology Case Report Abstract  Hepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH) are the most common pulmonary vascular complications in patients with liver disease. We present a 71-year old woman with alcoholic cirrhosis and 6 month history of progressive shortness of breath with mild hypoxemia at rest. Results of spirometry was normal and diffusing capacity of the lung for carbon monoxide (DLCO) was severity reduced. Echocardiography with contrast enhancement revealed extra cardiac shunt. Three months after her initial presentation, a new echocardiography was performed with pulmonary systolic pressure increased and in a right heart catheterization (RHC) the mean pulmonary arterial pressure (PAPm) was 50 mmHg, this evidence supported the diagnosis of severe portopulmonary hypertension after HPS. http://www.peertechz.com/Clinical-Microbiology-Biochemical-Technology/pdf/JCMBT-2-107.pdf

Vitamin D Deficiency: A Global Health Problem

Peertechz Journal of Environmental Science and Toxicology Short Communication Abstract  Vitamin D deficiency is a global health problem. The extent of vitamin D deficiency varies with latitude, season and sun exposure. Also the degree to which the body of religious or cultural reasons is covered, the skin color and, not least, dietary habits and the use of supplements has an impact on the vitamin D status. Women are more prone to develop vitamin D deficiency than men.   http://www.peertechz.com/Environmental-Science-Toxicology/pdf/PJEST-1-104.pdf  

Plavix versus Low Dose Aspirin Impact on Blood Flow of the Uterine Artery in Women with Unexplained Recurrent Miscarriage

Journal of Gynecological Research and Obstetrics Case Report Abstract Objective:   To evaluate Plavix impact on the perfusion of the uterine artery compared to low dose aspirin in women with unexplained recurrent miscarriage. Patients and Methods:   It was a prospective case control study that was carried out at Ain Shams University Maternity Hospital and included women who were presented to the outpatient clinic hospital department due to unexplained recurrent miscarriage. This study was performed over a 2-year period, between January 2014 and January 2016. 105 patients were recruited and divided into two arms. http://www.peertechz.com/Gynecological-Research-Obstetrics/pdf/JGRO-2-108.pdf