Synthesis and Antimicrobial Evaluation of Some Nitro-Mannich Bases Derived from β-Nitrostyrene

Peertechz Journal of Medicinal Chemistry and Research
Research Article
Abstract 
The present work focused on exploring the reactivity of β-nitrostyrene towards Mannich reaction with different approaches. The synthesized nitro-Mannich bases were tested as antimicrobial agents that showed high activity against both gram positive and gram negative bacteria.

http://www.peertechz.com/Medicinal-Chemistry-Research/pdf/PJMCR-1-103.pdf

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