Role of Inhalant and Food Allergens in Child Sensitization: A Prospective Study in 176 Children
Scientific Journal of Genetics and Gene Therapy
Research Article
Abstract
Background: The origin of atopic disease is poly factorial and the development of atopic manifestations appears to be linked to interactions between genetic and environmental factors. Such data seem to focus attention on the rising prevalence rates of atopic dermatitis, a common debilitating skin condition in infants and young children. They also often have asthma and/or allergic rhinitis.
Patients and Methods: The aim of the present study was to evaluate the rate of SPT (skin prick
tests) and RAST response to Der p in atopic children with AD. We have prospectively studied 176 children (93 males and 83 females) aged from 6 months to 7 years, and divided into four different groups, including controls. We studied also their family history in the accompanying
parents Results. The data of the present study show that a significantly higher proportion of children with AD have positive SPTs to Der p than the controls, while RAST was positive in a lower proportion of babies. A significant part of the parents had a positive atopic history.
http://www.peertechz.com/Genetics-Gene-Therapy/pdf/SJGGT-1-105.pdf
Research Article
Abstract
Background: The origin of atopic disease is poly factorial and the development of atopic manifestations appears to be linked to interactions between genetic and environmental factors. Such data seem to focus attention on the rising prevalence rates of atopic dermatitis, a common debilitating skin condition in infants and young children. They also often have asthma and/or allergic rhinitis.
Patients and Methods: The aim of the present study was to evaluate the rate of SPT (skin prick
tests) and RAST response to Der p in atopic children with AD. We have prospectively studied 176 children (93 males and 83 females) aged from 6 months to 7 years, and divided into four different groups, including controls. We studied also their family history in the accompanying
parents Results. The data of the present study show that a significantly higher proportion of children with AD have positive SPTs to Der p than the controls, while RAST was positive in a lower proportion of babies. A significant part of the parents had a positive atopic history.
http://www.peertechz.com/Genetics-Gene-Therapy/pdf/SJGGT-1-105.pdf
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