First and Second Line Highly Active Anti-Retroviral Therapy Failure in HIV Infected Nigerian Children at University of Abuja Teaching Hospital, Nigeria

Journal of HIV for Clinical and Scientific Research

Research Article

Abstract 
Background: In high-income countries, viral load is routinely used for monitoring HIV patients on antiretroviral therapy for early detection of drug failure. This is not the case in most resource limited settings like ours where only WHO immunological and clinical criteria are used for monitoring. This study is aimed at determining the rate/time of failure to 1st and 2nd antiretroviral drugs in children in our centers. Method: Is a retrospective study of children ≤18 years switched to 2nd line antiretroviral regimen and those requiring third line drugs from Jan 2006 to June 2015 in our health institution. Data analysis was conducted using SPSS version 16.0 software and statistical significance set at p < 0.05.

http://www.peertechz.com/HIV-Clinical-Scientific-Research/pdf/JHCSR-2-114.pdf

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