International Journal of Clinical Endocrinology and Metabolism
Case Report
An Analytical Study for Early Diagnosis and Treatment of Infants & Children Suffering From Congenital Hypothyroidism in China
http://www.peertechz.com/Clinical-Endocrinology-Metabolism/pdf/IJCEM-1-105.pdf
Case Report
An Analytical Study for Early Diagnosis and Treatment of Infants & Children Suffering From Congenital Hypothyroidism in China
Objective:
To study the clinical and laboratory
characteristics of children suffering from congenital hypothyroidism in China.
Method: 455 cases of congenital hypothyroidism infants were collected from
5 articles were published in 4 china medical journals. Different screening
methods were adopted, like enzyme immunoassay assay and filter paper dried
blood biotin-avidin enzyme notation to
test TSH, FT3、FT. All the collected children treated
by oral thyroxin tablets for long period and regular follow-up was done. Clinical follow up
for any signs of hypothyroidism and also detection of I.Q of those children.
Results: Markedly effective group: IQ >70%, height, constipation, lethargy,
abdominal distension, jaundice and other symptoms and signs were improved after
treatment. Effective group: IQ: 30%-70%, height, constipation, lethargy,
abdominal distension, jaundice and other symptoms and signs were improved after
treatment. Poor effective group: 0-30% IQ, while other signs and symptoms not
much improved. Laboratory testing revealed au thyroid along with oral treatment
of thyroxin in regular time and dose.
Conclusion:
Congenital hypothyroidism is a preventable
disease if early diagnosis and treatment was done.http://www.peertechz.com/Clinical-Endocrinology-Metabolism/pdf/IJCEM-1-105.pdf
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