Global Journal of Biotechnology and Biomaterial Science

Figure 1: Average of tail length lymphocytes of people living nearby of Santiago River and lymphocytes of healthy young volunteers exposed in vitro to polluted waters.

RESEARCH ARTICLE

Use of Comet Assay in Human Lymphocytes as a Molecular Biomarker for Simultaneous Monitoring of Genetic Damage and Genotoxicity in Residents Who Lived Nearby the Santiago River, Mexico, in 2012

Most aquatic and health management authorities need assessing the potential genotoxicity of contaminated effluent to avoid the effects of a lot chemical agents found as environmental contaminants. Previous studies report the presence of some pesticides and heavy metals in waters of Santiago River and suggest a genetic risk for residents, who lived nearby this river, so it is important determine its mutagenic risk. The objective of this study was to use of comet assay in human lymphocytes as a molecular biomarker of genetic damage in residents who lived nearby the Santiago River, Mexico, in 2012 and monitoring simultaneous of genotoxicity of these waters in unexposed persons. The genotoxic activity of water samples taken from the Santiago River was evaluated in human lymphocytes from persons unexposed and the evaluation of genetic damage were studied in people living near the river. The results indicated the existence of mutagens in the water (p ≤ 0.05), genetic damage statistically significant (p ≤ 0.05) in residents who lived nearby the Santiago River and carcinogenic risk to human health. The comet assay system in human lymphocytes can be used as a molecular biomarker for simultaneous monitoring of genetic damage and genotoxicity in aquatic environments contaminated with genotoxic, additionally this bioassay is reliable and inexpensive.

 http://www.peertechz.com/Biotechnology-Biomaterial-Science/GJBBS-1-102.php

Comments

Post a Comment

Popular posts from this blog

Case Report: Reynolds Syndrome

International Journal of Dermatology and Clinical Research Case Report Reynolds et al. described in 1971, 6 patients with classical primary biliary cholangitis, who presented concomitantly with varying degrees of scleroderma. Since then this association has been called Reynolds Syndrome.  https://www.peertechz.com/articles/case-report-reynolds-syndrome.pdf  #ReynoldsSyndrome#
Read more

Successful treatment of Budd- Chiari Syndrome with Percutaneous transluminal Balloon Angioplasty

Journal of Cardiovascular Medicine and Cardiology Case Report Introduction: Budd-Chiari syndrome (BCS) is a relatively rare disease in which an obstruction of hepatic venous outfl ow causes intrahepatic venous congestion and portal hypertension.     https://www.peertechz.com/articles/successful-treatment-of-budd-chiari-syndrome-with-percutaneous-transluminal-balloon-angioplasty.pdf
Read more

Ministernotomy Thymectomy in Mysthania Gravis-Future

Journal of Cardiovascular Medicine and Cardiology Research Article A thymectomy is the surgical removal of the thymus gland. The thymus has been demonstrated to play a role in the development of MG. It is removed in an effort to improve the weakness caused by MG, and to remove a thymoma if present.About 10% of MG patients have a tumor of the thymus called a thymoma. https://www.peertechz.com/articles/ministernotomy-thymectomy-in-mysthania-gravis-future.pdf  
Read more