International Journal of Pharmaceutical Sciences and Developmental Research

Research Article

 

A Pharmacokinetic Analysis and Pharmacogenomic Study of 6-mercaptopurine

Background: The efficacy and safety of 6-mercaptopurine (6-MP) therapy rely on the concentration of its metabolites. The aim of the current study is the pharmacokinetic analysis of 6-MP and the detection of its metabolites as well as the role of Thiopurine S-methyl transferase (TPMT), the enzyme associated with 6-MP metabolism, as a pharmacogenomics biomarker.

http://www.peertechz.com/Pharmaceutical-Sciences-Developmental-Research/IJPSDR-1-102.php

 

Comments

Post a Comment

Popular posts from this blog

Successful treatment of Budd- Chiari Syndrome with Percutaneous transluminal Balloon Angioplasty

Journal of Cardiovascular Medicine and Cardiology Case Report Introduction: Budd-Chiari syndrome (BCS) is a relatively rare disease in which an obstruction of hepatic venous outfl ow causes intrahepatic venous congestion and portal hypertension.     https://www.peertechz.com/articles/successful-treatment-of-budd-chiari-syndrome-with-percutaneous-transluminal-balloon-angioplasty.pdf
Read more

Case Report: Reynolds Syndrome

International Journal of Dermatology and Clinical Research Case Report Reynolds et al. described in 1971, 6 patients with classical primary biliary cholangitis, who presented concomitantly with varying degrees of scleroderma. Since then this association has been called Reynolds Syndrome.  https://www.peertechz.com/articles/case-report-reynolds-syndrome.pdf  #ReynoldsSyndrome#
Read more

Ministernotomy Thymectomy in Mysthania Gravis-Future

Journal of Cardiovascular Medicine and Cardiology Research Article A thymectomy is the surgical removal of the thymus gland. The thymus has been demonstrated to play a role in the development of MG. It is removed in an effort to improve the weakness caused by MG, and to remove a thymoma if present.About 10% of MG patients have a tumor of the thymus called a thymoma. https://www.peertechz.com/articles/ministernotomy-thymectomy-in-mysthania-gravis-future.pdf  
Read more