Global Journal of Obesity, Diabetes and Metabolic Syndrome
Editorial
Shaping Immune Responses by Dysregulatedadipokinesin Obesity
Obesity inhibits MHCII expression on macrophages and lowers the percentage of T cells in lymph nodes and spleen.
A, a representative flow cytometric staining of CD4+ and CD8+ T cells in lymph nodes (LNs) from mice with normal-fat diet (NF) or high-fat diet (HF).
B, average percentage of CD4+ and CD8+ T cells in LNs and spleen from LF or HF mice.
C, flow cytometric analysis of MHCII expression on macrophages in bone marrow (BM) from NF or HF mice.
D, mean fluorescent intensity (MFI) of MHCII expression on macrophages in BM from NF or HF mice (*, p<0.05; **, p<0.01 as compared to NF group).
A, a representative flow cytometric staining of CD4+ and CD8+ T cells in lymph nodes (LNs) from mice with normal-fat diet (NF) or high-fat diet (HF).
B, average percentage of CD4+ and CD8+ T cells in LNs and spleen from LF or HF mice.
C, flow cytometric analysis of MHCII expression on macrophages in bone marrow (BM) from NF or HF mice.
D, mean fluorescent intensity (MFI) of MHCII expression on macrophages in BM from NF or HF mice (*, p<0.05; **, p<0.01 as compared to NF group).
http://www.peertechz.com/Obesity-Diabetes-Metabolic-Syndrome/GJODMS-1-106.php
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