Heredo-Familial and Pediatric Gists: Spot the Differences

Scientific Journal of Genetics and Gene Therapy

 Review Article

 Gastrointestinal stromal tumors (GISTs) are rare sporadic tumors that typically occur late in life, although they are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs are believed to originate from the Interstitial Cells of Cajal (ICC), a group of cells identified in the wall of the organs of the gastrointestinal tract, which act as a pace-maker for peristalsis and gut movements. However, familial and pediatric cases have also been reported.

http://www.peertechz.com/Genetics-Gene-Therapy/pdf/SJGGT-2-107.pdf

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