Peertechz Publications

International Journal of Clinical Endocrinology and Metabolism Case Report Abstract  Thyroid hormones are important for early brain development. During pregnancy, both maternal and foetal thyroid hormones contribute to foetal brain development. Maternal Graves’ can lead to transplacental transfer of antibodies that cause neonatal thyrotoxicosis. Neonatal thyrotoxicosis is rare and a high index of suspicion is needed to diagnose it. Neonatal thyrotoxicosis has significant risk of morbidity and mortality and early recognition is warranted. Babies who are at risk following birth should be identified early while avoiding the need for unnecessary blood tests or prolonged hospital admission. There are no published consensus guidelines to date as to how these babies should be managed and followed up. The purpose of this guideline is to describe the importance of risk stratification and subsequent management of babies born to mothers with a history of Graves’ disease. http://www.peertechz

Journal of Addiction Medicine and Therapeutic Science Editorial During the past 20 years I’ve been in practice, I have found that all addiction treatments are, in fact, some form of harm reduction. We’ve yet to find an infallible treatment for addictions and substance use disorders. However, the change in the DSM terminology is very significant. It differentiates diagnoses of substance abuse and chemical dependency from its evolved diagnosis of substance use disorder - mild, moderate or severe. Those with severe diagnoses (co-morbidity involving diabetes, liver damage, severe psychiatric conditions, dementia, legal, etc) would certainly be appropriate candidates for abstinence over moderation. But as I see it, at the end of the day, from moderation to abstinence it’s all harm reduction. http://www.peertechz.com/Addiction-Medicine-Therapeutic-Science/pdf/JAMTS-2-112.pdf

Journal of Addiction Medicine and Therapeutic Science Research Article Abstract  Background: Methamphetamine abuse and dependence is currently a considerable problem. Objective: To explain the efficacy of buprenorphine in the quick management of methamphetamine related anxiety and depressive disorders and also methamphetamine withdrawal craving. Results: 52 mg of buprenorphine is very valuable in the treatment of severe methamphetamine related anxiety and depression and also methamphetamine craving. Discussion: This study lightens that high dose of buprenorphine is quite effective in the lowering of anxiety, depression, and chest pain and methamphetamine withdrawal symptoms. Hence, our finding is a substantial addition to the literature. Conclusions: We resulted that a single high dose of buprenorphine could quickly subside methamphetamine induced anxiety, depression, psychogenic pain and withdrawal symptoms. It looks that buprenorphine may be a safe and valuable drug for the treat

Global Journal of Obesity, Diabetes and Metabolic Syndrome Review Article Abstract  Introduction: Catalase decomposes hydrogen peroxide into oxygen and water. Its low concentration could be involved in signaling while its high concentration is toxic. Aim: This short review discusses the association of blood catalase and diabetes mellitus in Hungarian diabetic patients. Results: Several cohort studies showed decreased blood catalase activity in type 2 diabetes and in gestational diabetes. Among the catalase gene polymorphisms rs769217 showed a weak association with type 1 diabetes. Regarding rs1001179 polymorphism patients with TT genotype have a risk for lower life expectancy. http://www.peertechz.com/Obesity-Diabetes-Metabolic-Syndrome/pdf/GJODMS-3-111.pdf

Archives of Depression and Anxiety Review Article Abstract  Music has long been regarded to aid health and loss-adaptation, but effect of music intervention on cancer patients is not well-understood. The aims of this study are to summarize and describe the role of music before and after diagnosis. This review examines music intervention studies with randomized designs for patients with cancer published between 1991 and 2015 from three Englishlanguage databases and Chinese-language databases. Ten studies that met specific inclusion criteria were reviewed. Our review indicates that music intervention may have beneficial effects on emotion (anxiety/depression) in patients with cancer. More research is needed to ascertain the most optimal intervention methodology on which cancer populations or which treatment modalities are appropriate for such an intervention. http://www.peertechz.com/Depression-Anxiety/pdf/ADA-2-107.pdf

Archives of Otolaryngology and Rhinology Case Report Introduction  Tertiary syphilis shows most marked manifestations in the nose causing superficial and deep ulcerations and gumma. Gummatous deposit may occur in any portion of the nose. The deformity resulting from the destruction of the bony frame work of the nose and the shrinking of fibroid tissue produces typical saddle nose which is characteristic of syphilis. It is important to establish the diagnosis after carefully ruling out other clinical possibilities and confirming Treponemal infection by laboratory evaluation. The respiratory tract, next to skin, furnishes the most frequent manifestations of syphilis. http://www.peertechz.com/Otolaryngology-Rhinology/pdf/AOR-2-114.pdf

Global Journal of Allergy Research Article Abstract  The distribution of fish species in Jemma and Wonchit Rivers was studied from November 2012 to May 2014 based on samples collected during wet and dry seasons using gillnets of 60, 80, 100, 120 and 140 mm stretched mesh sizes. Labeobarbus intermedius, Labeobarbus nedgia, Heterobranchus longifilis, Bagrus docmak, Varicorhinus beso and Oreochromis niloticus are commercially important fish species found in both rivers of the pooled experimental fish catch. But, Synodontis schall, Ramias loti, Labeo forskhalii, Tilapia rendelii, Mormyrus kannume and Bagrus bajad are found in river Jemma only. The high level of pH in Wonchit (9.14) may be lethal for some of the fishes that found in the river. The pH in Jema (8.79) might indicate higher productivity of water, but it is very approximate to the higher limit. The most likely explanations for the fishing activity of fish species are the increase of the illegal commercial plant poisoning mat

Global Journal of Allergy Review Article Abstract Nocturnal asthma is defined by a drop in forced expiratory volume in 1 second (FEV1) of at least 15% between bedtime and awakening in patients with clinical and physiologic evidence of asthma. Nocturnal asthma is associated with a circadian pattern in lung function, distal airway inflammation, glucocorticoid receptor affinity, pulmonary capillary blood volume, and beta-2 adrenergic receptor function may also contribute. Knowledge of these characteristics, along with an understanding of the specific therapies directed at the circadian nature of this disease, can result in significant improvements in lung function, sleep quality, and asthma related quality of life. http://www.peertechz.com/Allergy/pdf/Allergy-2-112.pdf  

Global Journal of Anesthesiology Editorial The use of brain stimulation either without drugs at all or with ones that are currently obsolete for the promotion of general anesthesia [1]. Furthermore, different intensities and time durations of stimulation were reported, making it difficult to compare between studies. In the past few decades, there has been an intensive development in the techniques of neurostimulation [2], including the use for chronic pain management [3]. Although it has not been assessed for general anesthesia anymore, current data on brain stimulation suggests that low intensity electric currents may have mechanisms that could be useful as an add-on therapy in anesthesia; this supports ethical and well-designed experimental and clinical studies focusing on their anesthetic and analgesic effects. http://www.peertechz.com/Anesthesiology/pdf/GJA-3-122.pdf

Archives of Community Medicine & Public Health Mini Review Sustainability could be considered a buzzword of current health care practice but finally it need develop activities having sustainability as goal [1]. http://www.peertechz.com/Community-Medicine-Public-Health/pdf/ACMPH-2-108.pdf

Journal of Gynecological Research and Obstetrics Research Article Objectives: To assess the accuracy of 5D automated measurement of long bones, three dimensional VOCAL measurement of fetal thigh volume in prediction of fetal weight in comparison to the conventional two dimensional Hadlock formulas. http://www.peertechz.com/Gynecological-Research-Obstetrics/pdf/JGRO-2-111.pdf

Journal of Gynecological Research and Obstetrics Research Article Objective: To assess the response and evolution of vaginal intraepithelial neoplasia (VAIN) after CO 2 laser treatment. Material and Methods: A retrospective study was conducted from a database of 139 women who had VAIN and were referred for treatment with CO 2 laser. The lesions were detected following a hysterectomy. Human papillomavirus (HPV) typification was performed in all cases. http://www.peertechz.com/Gynecological-Research-Obstetrics/pdf/JGRO-2-110.pdf 

Global Journal of Cancer Therapy Research Article Background: Despite the crucial role of integrin receptors in cancer pathogenesis and massive efforts towards establishing clinically relevant drugs, to the present no effective integrin antagonist for the treatment of malignant diseases has been introduced into the clinic. http://www.peertechz.com/Cancer-Therapy/pdf/GJCT-2-108.pdf

Global Journal of Anesthesiology Case Report This case report describes an unusual presentation and anesthesia management of a rare genetic association. The MURCS association, a variant of Mayer-Rokitansky-Kuster-Hauser syndrome is a rare (1/4500-1/50,000) congenital syndrome, of unknown etiology, consisting of mullerian duct (MU) aplasia, renal (R) aplasia, and cervicothoracic somite (CS) dysplasia. http://www.peertechz.com/Anesthesiology/pdf/GJA-3-121.pdf

Archives of Pulmonology and Respiratory Care Research Article Abstract Background/Objectives: The association between asthma and mental health disorders is well known, both anxiety and depression being the most common ones. The aim is to determine the proportion of anxiety and/or depression in an asthmatic population compared to a non-asthmatic one in a Primary Care centre. Secondary objectives: Assess the association between the severity of asthma and its level of control and anxiety and/or depression. www.peertechz.com/Pulmonology-Respiratory-Care/pdf/APRC-2-109.pdf

Peertechz Journal of Cytology and Pathology Research Article Introduction: Diabetes Mellitus (DM) is associated with long-term damage, dysfunction, and failure of various body organs. Glycosylated haemoglobin (GHbA1c) is a significant biochemical marker in patients with DM which provides an estimation of long-term average glycaemia. The aim of this study was to evaluate the relation between fasting serum glucose (GLU) level and GHbA1c in DM patients and healthy controls, to evaluate the differences between male and female patients and to evaluate the correlation between estimated Average Glucose (eAG) and GLU. http://www.peertechz.com/Cytology-Pathology/pdf/PJCP-1-104.pdf    

International Journal of Oral and Craniofacial Science Research Article Abstract Background: Oral cancers are mostly being preceded by oral potentially malignant disorders (OPMD). Early diagnosis of oral cancer or OPMDs speed up treatment and improve prognosis. Raman spectroscopy of blood, urine, saliva and tissue samples collected from OPMD and oral cancer patients were compared with similar samples from normal controls.   http://www.peertechz.com/Oral-Craniofacial-Science/pdf/IJOCS-2-113.pdf 

International Journal of Aquaculture and Fishery Sciences Research Article Abstract Background and aim: Stomatorhinus cf polli , one of species of Mormyridae whose flesh is highly appreciated by local communities. Unfortunately, there is very little information about biology and ecology of Stomatorhinus cf polli . This study aimed to determine the ecology and biology of Stomathorinus cf polli . http://www.peertechz.com/Aquaculture-Fishery-Sciences/pdf/IJAFS-2-111.pdf  

Global Journal of Cancer Therapy Mini Review Abstract  26S proteasome is an intracellular; ATP dependent enzymatic complex degrades ubiquitin-tagged proteins and maintains cellular homeostasis. The orderly degraded proteins including cyclins, caspases, Bcl-xL, p53, cell adhesion molecules are involved in cell-cycle progression, tumor suppression, DNA replication, inflammation, and apoptosis. So, proteasome inhibition is a target therapy for cancer to promote cell cycle arrest or apoptosis. Bortezomib (Velcade®, PS-341, and Millennium Pharmaceuticals, Inc.) is the first, selective, reversible, and only proteasome inhibitor for the treatment of multiple myeloma have been approved by U.S. Food and Drug Administration (FDA) in 2003. Bortezomib downregulates the interaction of multiple myeloma cells with bone marrow stromal cells, inhibits angiogenesis, and blocks cell cycle progression. Clinically, continuous dosage of bortezomib leads to few side effects . http://www.peertechz.com/Ca

Archives of Pulmonology and Respiratory Care Case Report Abstract  Pulmonary blastomas are a rare aggressive neoplasms comprising 0.25-0.5% of all primary lung tumors and portend a poor prognosis. Recent World Health Orgnisation (WHO) reclassifications separated well differentiated fetal adenocarcinoma and pleuropulmonary blastoma from classic biphasic pulmonary blastoma which is now among carcinomas with pleomorphic, sarcomatoid or sarcomatous elements. The clinical and radiologic features are nonspecific. Surgery is the standard treatment and the efficacy of adjuvant chemotherapy and radiotherapy has not yet been established. We present a case of classic biphasic pulmonary blastoma in a 52-year old male and review the literature.   http://www.peertechz.com/Pulmonology-Respiratory-Care/pdf/APRC-2-108.pdf 

Archives of Clinical Gastroenterology Research Article Abstract  Background: Gastric adenocarcinoma is the fourth most common malignancy worldwide and is globally the second leading cause of cancer-related deaths each year. Salted foods and exposure to H. pylori infection during the infancy have been considered the most important environment risk factors for gastric cancer. Despites increased access to electric energy, allowing the use of refrigerators to better conserve foods, many people keep consuming salted food, by washing them before eating with the intention of reducing salted flavor and also supposing to decrease or avoid risk of diseases. The aim of this study was to investigate the efficacy of reducing nitrites levels in salted fish by washing the fish before consuming, to find if washing salted food should be an efficient measure to reduce, or even avoid, the nitrites related gastric cancer risk. Methods: Nine paired samples of fresh and salted fish and 20 additional sam

International Journal of Oral and Craniofacial Science Research Article Abstract In several diseases, fractal analysis has been proven useful to give contribution in diagnosis and prognosis of the patient and to improve treatments. In the present work we have evaluated the mass dimension of the vascular pattern of optic nerve head in non-glaucomatous optic neuropathic patients and healthy controls. Static fluorescein angiogram was performed and the images of the early venous phase were saved. A manual outline of the trajectories of the two-dimensional vascular network was performed down to vessels of 20 um diameter, processed to threshold the vessel network without background interference and converted into an outline of single pixels and then the fractal analysis was performedMass dimension evaluation of the optic nerve head microvascularity was able to differentiate health condition vs. non-glaucomatous neuropathies (p<0.01), as well optic neuritis vs. nonarteritic anterior is

Journal of Gynecological Research and Obstetrics Research Article Abstract  Objective: To explore the role of estimating endometrial volume by Virtual Organ Computer-aided AnaLysis (VOCAL) and it’s correlation with endometrial thickness, on the day of hCG, in prediction of IVF/ICSI success. Patients and Methods: It was a prospective study that was carried out at Al-Amin Maternity Hospital, Saudi Arabia. Endometrial thickness and volume were measured in women undergoing an IVF/ICSI cycle, on the day of HCG, using the 3D transvaginal ultrasound probe. Women were divided as regards to endometrial volume calculated into 3 subgroups; < 3ml, 3-5ml, and >5ml, also according to endometrial thickness into 3 groups; <7mm, 7-12mm and >12mm. Success rate of IVF/ICSI was compared between all groups. Results: The current study included 150 consented women with no significant difference in clinicdemographic characteristics between all subgroups. The pregnancy rates between the three g

Open Journal of Clinical Toxicology Case Report Abstract  Paracetamol is one of the most used drugs in the world. We report here two cases of children poisoning (less than 3 years old) who were accidentally administered an adult form of rectal suppository containing a combination of paracetamol-codeine (1000 mg/60 mg). The first child received a dose of 154 mg /kg of paracetamol and 9 mg/kg of codeine two times daily for 2 days. Clinical signs were vomiting and epigastric abdominal pains. Biochemistry showed an increase of liver enzymes (4 to 40 fold), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma glutamyl transpeptidase (GGT). The second child received the suppositories discontinuously (two times daily) and showed less severe signs of intoxication. The administration of N-acetylcysteine at admission into hospital limited the toxic effects of paracetamol. The toxic effects of codeine, such as central nervous system (CNS) depression were not obvious in b

Open Journal of Plant Science Research Article New o-benzoquinone and a C16 long-chain para-coumarate ester were isolated from Lonchocarpus nicou roots. Their structural elucidations are based on different spectroscopic data analysis. In addition, the known pterocarpanoids maackiain and flemichapparin-B never reported in L. nicou were also isolated along with rotenone, the major phytochemical from this tropical liana.   http://www.peertechz.com/Plant-Science/pdf/OJPS-1-101.pdf