International Journal of Pharmaceutical Sciences and Developmental Research

Research Article

 

A Pharmacokinetic Analysis and Pharmacogenomic Study of 6-mercaptopurine

Background: The efficacy and safety of 6-mercaptopurine (6-MP) therapy rely on the concentration of its metabolites. The aim of the current study is the pharmacokinetic analysis of 6-MP and the detection of its metabolites as well as the role of Thiopurine S-methyl transferase (TPMT), the enzyme associated with 6-MP metabolism, as a pharmacogenomics biomarker.

http://www.peertechz.com/Pharmaceutical-Sciences-Developmental-Research/IJPSDR-1-102.php

 

Comments

Post a Comment

Popular posts from this blog

Case Report: Reynolds Syndrome

International Journal of Dermatology and Clinical Research Case Report Reynolds et al. described in 1971, 6 patients with classical primary biliary cholangitis, who presented concomitantly with varying degrees of scleroderma. Since then this association has been called Reynolds Syndrome.  https://www.peertechz.com/articles/case-report-reynolds-syndrome.pdf  #ReynoldsSyndrome#
Read more

Apparent Digestibility and Utilization of Protein and Phosphorus in diets of incorporated with Sprouted Sorghum, Phytase and Protease Enzymes for African Catfi sh (Clarias gariepinus)

International Journal of Aquaculture and Fishery Sciences Research Article Apparent digestibility, deposition and retention of crude protein and phosphorus were determined for 30%, 35%, 50% and 55% CP diets incorporated with sprouted sorghum, 750, 1000 and 1250 unitskg-1 phytase and protease enzymes ,fed to African catfish fingerlings. ... https://www.peertechz.com/articles/characteristics-and-status-of-the-highland-lake-hashenge-fishery-tigray-northern-ethiopia.pdf  
Read more
Journal of Gynecological Research and Obstetrics Research Article Prevention of Brachial Plexus Injuries at Birth Medicine is a fast evolving even if inexact science. Built in ancient times upon insightful observations of Egyptian, Greek and Arabic physicians [ 1 1. Lyons AS, Petrucelli RJ II (1978) Medicine. An Illustrated History. Harry N. Abrams, Inc., New York. ], its progress was spearheaded by European (mainly British, French, German and Austrian) scientists after the middle ages. If the assignment of Nobel prizes is a guideline is this regard, in the last century the leadership was taken over by the United States. Both physicians and lay persons may be inclined to assume therefore, that the achievements of medical research are utilized in America in everyday practice and that progress runs parallel in all branches of medicine. As far as obstetrics is concerned these assumptions have limited validity at best. During the last century maternal and perinatal morta...
Read more