Peertechz Publications

Journal of Surgery and Surgical Research Research Article Abstract  Background and purpose: During knee joint distraction (KJD) treatment, using an external fixation-frame, pin-tract infections frequently occur. These local skin infections, although treated successfully with oral antibiotics, might lead to latent infections. This raises concern about subsequent placement of a total knee prosthesis (TKP). This study evaluates the first five cases in which patients had to be treated with TKO after KJD failure. Patients and methods: An overall survival analysis of the first 26 patients treated with KJD revealed five failures, because of declining efficacy over time. These patients were treated with TKP. Complications of these TKPs are described and all cases were compared with age and gender matched primary-TKP-controls. WOMAC and VAS pain scores were assessed before and after TKP treatment. Results: The mean survival time of the five KJD before TKP was 61 ± 15 months (range 45-84...

Journal of Civil Engineering and Environmental Sciences Research Article Abstract  This paper aims to provide an innovative scenario for transportation and lowering installation of heavy caissons of 18000 tons for Persian Gulf Bridge. The project is supposed to be carried on in Bohal port from Hormozgan to Qeshm Island in Iran. There is a heated controversy over the suitable scenario to do the operation safely and lower the caissons correctly under sea to position them on their exact location. Due to this a comprehensive study is need to take heed all aspect of the operation. The study will include a discussion on both sides of installation and transportation and give a deep-rooted insight over the excuvation plane for the operation. http://www.peertechz.com/Civil-Engineering-Environmental-Sciences/pdf/JCEES-1-106.pdf

Archives of Clinical Nephrology Research Article Abstract Background: Acute renal failure (ARF) continues to be a challenging problem in critically ill patients. We reviewed the nephrology consultations in our ICU to assess the necessity of those consultations and if there are any clinical criteria to indicate a necessary consultation. Methods: Retrospective chart review of nephrology consultations for patients with ARF in our medical ICU from 2010 to 2011. After data collection we classified consultations to necessary versus unnecessary based on an experts review. We used chi square and multivariate logistic regression model to compare both groups Results: We found that 45% of patients with ARF admitted to the ICU received nephrology consultation. 32% were identified as unnecessary. Age, gender and etiology were similar in both groups. Oliguria independently predicted the need for nephrology consultation Conclusions: Oliguria predicted the need for nephrology consultation independ...

Global Journal of Cancer Therapy Editorial The financial crisis has a dramatic impact on social life, since reduced or even non-existent incomes affect people’s well-being and push big parts of the population to poverty. The individuals’ financial status affects health indicators such as life expectancy, morbidity, mortality and healthcare service accessibility [1].   http://www.peertechz.com/Cancer-Therapy/pdf/GJCT-1-105.pdf 

International Journal of Vascular Surgery and Medicine Clinical Image A 65 year old male presented to the causality department of our hospital with one day history of burning chest pain in the right upper half of the chest radiating to the right axilla & the left precordial region associated with diaphoresis. No history of fever, cough or rash was evident. Vitals were normal. An X ray chest done was normal and ECG showed RBBB (Figure 1). http://www.peertechz.com/Vascular-Surgery-Medicine/pdf/IJVSM-1-105.pdf

Global Journal of Obesity, Diabetes and Metabolic Syndrome Review Article Abstract  We report clinical and molecular mechanisms relating the pro-inflammatory and antiinflammatory process in the development of the components of the metabolic syndrome, emphasizing the cardiovascular problems developed in these groups of patients, especially the Hispanic population. Namely, the incidence, component characteristics and complications of the metabolic syndrome in island Puerto Ricans are described and evidence is presented supporting the fact that the metabolic syndrome may be milder in Puerto Rico than in the mainland United States because it is characterized by less aggressive coronary artery disease and a relatively normal lipid profile. Moreover, data supports the fact that increased serum cholesterol levels produce less myocardial infarctions in Puerto Rico than in mainland Hispanics and Caucasians. In addition, the incidence of ventricular tachycardia, a complication caused by ...

Global Journal of Infectious Diseases and Clinical Research Review Article Abstract  Objective: This article presents a literature review which relates the processes, interactions, classification and the vascular and clinical characteristics of inflammation relating it with the oral cavity and describing the main cell types and chemical mediators used for its establishment. Materials and Methods: it was used as source of research the following databases: MEDLINE, LILACS, BBO, Cochrane Library, Scielo, PubMed and the database of CAPES. Results: much information was obtained concerning the chemical mediators as well as the main cell types responsible for the establishment of inflammation and its relationships with the oral cavity. http://www.peertechz.com/Infectious-Diseases/pdf/GJIDCR-1-106.pdf

Journal of Dental Problems and Solutions Research Article Abstract  The aim of the present study was to compare the dental caries status of the 12 year old children of the eastern region of Macedonia and Budgam district of Jammu and Kashmir state of India. Material and Method: In this comparative study (N=396) 12-year old children from Macedonia and 592 from India were included. Dental status of participants was evaluated using the 2013 World Health Organization caries diagnostic criteria for Decayed, Missing or Filled Teeth (DMFT) by 2 calibrated examiners in Macedonia and by the single examiner in India. Results: The mean value of the DMFT index for the whole sample of India was 1.91 ± 1.76 whereas for Macedonia it was 3.46 ± 2.90, and the difference was statistically significant (p<0.001). In the Indian sample, 152 (25.68%) and in Macedonia sample 81 (21.46%) of the individuals were caries free (DMFT=0).In both countries, the female children have higher mean DMFT values. ...

Global Journal of Cancer Therapy Research Article Abstract  Eribulin sensitivity was examined in a panel of twenty-five human cancer cell lines representing a variety of tumor types, with a preponderance of breast and lung cancer cell lines. As expected, the cell lines vary in sensitivity to eribulin at clinically relevant concentrations. To identify combination drugs capable of increasing anticancer effects in patients already responsive to eribulin, as well as inducing de novo anticancer effects in non-responders, we performed a combinatorial high throughput screen to identify drugs that combine with eribulin to selectively kill tumor cells. Among other observations, we found that inhibitors of ErbB1/ErbB2 (lapatinib, BIBW-2992, erlotinib), MEK (E6201, trametinib), PI3K (BKM-120), mTOR (AZD 8055, everolimus), PI3K/mTOR (BEZ 235), and a BCL2 family antagonist (ABT-263) show combinatorial activity with eribulin. In addition, antagonistic pairings with other agents, such as a to...

Journal of Addiction Medicine and Therapeutic Science Case Report Abstract Background: Tramadol induced disorder is a new problem. Objective: To explain the efficacy of low dose of clonidine, baclofen and ibuprofen (NSAID) in the treatment of severe and chronic tramadol dependency (2000 mg daily). Method: To evaluate the usefulness of non-narcotic drugs in the management of severe tramadol withdrawal symptoms. Results: Clonidine 0.3 mg, baclofen75 mg and ibuprofen 1200 mg per day is very effective in the management of severe tramadol withdrawal symptoms and craving. Discussion: Our findings indicates that low dose of clonidine, baclofen and ibuprofen (NSAID) is beneficial in the treatment of severe tramadol dependency. This is a fascinating result. Conclusion: To our knowledge dramatic effects combination of clonidine, baclofen and ibuprofen in these situations has not been published yet, and this finding is a considerable addition to the literature.    http://www.peerte...

Archives of Community Medicine & Public Health Research Article Abstract  Background: In the past two decades negative attitudes towards vaccination has surfaced among parents. These concerns are related to safety, adverse effects, lifestyle and religious issues. The present study focuses on compensatory health beliefs (CHB), the beliefs that the adverse consequences of one health behavior are compensated by another health behavior, and examines whether CHB predicts behavior and mediates the association between the intention to vaccinate one’s children and vaccination behavior. Methods: Parents (n=90) to children up to 6 years old filled an online questionnaire taping intentions and behaviors to vaccinate, self-efficacy to vaccinate, compensatory health beliefs related to vaccination and lifestyle. Results: A significant negative association was found between CHB and intention to vaccinate and vaccination behavior (r=-0.69, p<.01), and a non-significant positive associat...

International Journal of Immunotherapy and Cancer Research Research Article Abstract  Background: VEGF is involved in cancer development by stimulating neo-angiogenesis and tumor proliferation. Anti-angiogenic therapies, especially tyrosine kinase inhibitors such as sunitinib, have significantly improved cancer prognosis. Nevertheless, renal side effects, such as proteinuria and thrombotic microangiopathy, have been reported. The underlying physiopathological mechanisms remain unclear, but animal models and clinical similarities with preeclampsia suggest that such therapies affect the function of the endothelial and epithelial layers of the glomerular basement membrane, with activation of the endothelin signaling system and loss of glomerular slit diaphragm integrity. The aim of this in vitro study was to determine sunitinib effects on normal podocytes and glomerular endothelial cells. Methods: The glomerular microvascular endothelial (GMVEC) and human glomerular visceral epith...

Journal of Surgery and Surgical Research Research Article Summary  Indroduction: Neuroendocrine tumors (NEN) of the gastro-entero-pancreatic tract (GEP) are a group in themselves very heterogeneous of tumors that are different for the site of localization in the digestive tract (foregut, midgut and hindgut), both in relation to the pathological aspects, functional activity and nosographic classification. Materials and methods. In the period from January 2001 to July 2006 (III Clinical Surgery unit) and from January 2006 to October 2013 (Surgery of the Digestive Tract Unit), UOCS of the University Hospital of Catania has come to our observation 4 patients in the first period and six in the second period. Cases of NEN-GEP we observed allow to highlight how there are elements of clinical differences that make it difficult framing them. Results: Are summarized personal pathologic and therapeutic results. Discussion: The interest in the subject stems also from the fact that tumors N...

Journal of Surgery and Surgical Research Research Article Abstract Background: To investigate clinic-pathological characteristics, hormonal receptors and HER2 receptor of male breast cancer. Materials and methods: Retrospective study of 10 cases between 2010 and 2013. The studied parameters were: tumor size, histological type, histological grade, lymph node status, hormonal status and overexpression of HER2. Results: The average age of our patients was 60.2 years, in 70% of cases; the histological size that was found was T4; and infiltrating ductal carcinoma was diagnosed in all cases. The grades classification was as follow: grade 2 (30%) and grade 3 (70%). 70% of cases had lymph node metastasis. Estrogen and progesterone receptors (ER,PR) were positive in 60% of tumors. Overexpression of HER2 was positive (Score3) in one case. Luminal B was the most common subtype in our study. Conclusion: Male breast cancer is a rare disease with a poor prognosis despite the recent increase in i...

Journal of Surgery and Surgical Research Case Report Abstract  Abstract Cystic Echinococcosis (CE) is a zoonotic infection caused by larval form of the parasite Echinococcus granulosus. The adult tapeworm inhabit the small intestine of some carnivores (called definitive or final hosts), and the larval phase, or “metacestode” develops in the herbivores (intermediate hosts). The presentation form of the larval phase is the development of cysts, called hydatid cysts. Although all of us know the vital cycle of the parasite and the different aspects of the disease, the designations around the parasite, its evolution and some therapeutic procedures is not uniform. In fact we frequently see the use of inappropriate terms, based on incorrect concepts. It would be useful to use the same nomenclature and it is absolutely necessary that the nomenclature is correct and universally accepted. So, it is pertinent to remember some important points related to the CE and, above all, to clarify s...

Journal of Civil Engineering and Environmental Sciences Research Article Abstract  Cultural barrier is always perceived as the prime challenge for modernizing idle construction markets. Unsurprisingly, most changes in construction hinge on understanding the benefits of sustainable transformation. Persistent attempts in stagnant construction cultures have materialized in some noted changes. Successful sustainable transformation in such economies appears to be chiefly impeded at the execution level. The Kotter’s model for change is globally accepted approach for comprehensive implementation of major business transformations. Modern organizational change initiatives typically embrace the notions of Six Sigma in a broader sense. This concept paper propose the use of Six Sigma DMAIC technique for reforming stagnant construction cultures. A case study from a challenged construction market is referred to for potential implication.    http://www.peertechz.com/Civil-Engineer...